A Comprehensive List of Nootropics: Mind-Boosting Supplements and Drugs

Nootropics, sometimes called “smart drugs,” are substances that are claimed to improve cognitive function. Nootropics are becoming an increasingly popular way to boost mental performance, and there is a wide variety of different substances that fall into this category.

This comprehensive list will outline all of the most important nootropics, including their key benefits and side effects. If you’re looking to give your mind an extra edge, then read on!

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5-HTP

Safe and effective serotonin support for mood and sleep
Other Names: 5-Hydroxytryptophan

5-HTP, or 5-hydroxytryptophan, is a natural supplement that is typically used to treat symptoms of depression and anxiety. It is believed to work by affecting the levels of serotonin in the brain, which is a neurotransmitter that helps regulate mood and emotions.

The origins of 5-HTP can be traced back to the 1960s, when it was first discovered and studied by scientists. Since then, it has become widely used as an alternative treatment for various mental health conditions, including depression, sleep disorders, and obsessive-compulsive disorder (OCD).

There are several different ways that 5-HTP can be used to help treat these conditions. For example, it may be taken on its own in capsule or tablet form as a dietary supplement. Additionally, it can be administered along with other medications for more effective treatment.

Overall, 5-HTP is considered to be a safe and effective way to manage symptoms of depression and anxiety without the potential side effects associated with some traditional treatments like antidepressants.

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Acetyl L-Carnitine (ALCAR)

The Red Meat Amino
Other Names: ALCAR, L-Carnitine, Acetyl L-Carnitine

Acetyl L-Carnitine, also known simply as ALCAR, is a naturally occurring amino acid that is commonly used as a dietary supplement. Originating from animal sources like beef and milk, this compound has long been used in traditional medicine to help treat various symptoms and conditions. Today, it is widely used for a variety of purposes, including promoting heart health, boosting energy levels, and improving cognitive function.

Some of the main benefits of ALCAR supplementation include increased metabolism, increased insulin sensitivity, reduced fatigue and muscle soreness after workouts, and improved memory and focus. Additionally, because this compound is thought to have anti-aging properties, it has become popular among those looking to improve their overall health and wellbeing over time.

Overall, if you are looking for a safe and effective way to boost your health and wellbeing through natural means, then ALCAR may be a good option for you. However, it is always important to consult with a healthcare professional before beginning any new supplement regimen.

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Adrafinil

A legal over-the-counter version on Modafinil
Other Names: Olmifon

Adrafinil is a popular nootropic supplement that was originally developed in France in the 1970s as a treatment for narcolepsy. It works by increasing levels of several neurochemicals in the brain, including dopamine, norepinephrine, and serotonin. This helps to boost mental clarity and focus, as well as relieve symptoms of depression and anxiety.

Adrafinil is often used by people who want to improve their concentration and cognitive function, especially those suffering from age-related cognitive decline or disorders like ADHD or dementia. It is also commonly used as a study aid or to enhance athletic performance, due to its ability to improve energy levels and reduce fatigue.

In addition to these benefits, Adrafinil may also be used to treat certain sleep disorders such as REM behavior disorder or obstructive sleep apnea. While it has not been approved by the FDA for any medical purposes, it is generally considered safe when taken in recommended dosages. However, it should not be taken by individuals with liver disease or high blood pressure.

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Alpha-GPC

Great source of choline that works well in nootropic stacks
Other Names: L-Alpha glycerylphosphorylcholine, Choline Alfoscerate

Alpha-GPC, or alpha-glycerophosphocholine, is a supplement that is commonly used to treat a variety of symptoms and conditions. It is believed to have many beneficial effects on the body, including improving memory and focus, enhancing athletic performance, and reducing the risk of age-related health conditions like dementia and Alzheimer’s disease.

The origins of Alpha-GPC can be traced back to Europe in the 1950s, when it was first developed as a way to treat patients with neurological disorders like stroke and traumatic brain injury. Since then, its potential benefits have been investigated in numerous clinical trials and studies. Today, Alpha-GPC is typically marketed as a nootropic supplement used by both healthy individuals and those suffering from various cognitive conditions.

Some of the most common symptoms that Alpha-GPC is used for include memory loss, cognitive decline, attention deficit disorders (ADD/ADHD), depression, anxiety, and chronic fatigue syndrome. However, its effectiveness for these conditions remains unclear due to conflicting results from studies. Overall, more research into the benefits and safety of Alpha-GPC is needed in order to better understand its role in treating various health conditions.

Ampakines

Extremely potent synthetic nootropic
Other Names: CX compounds

Ampakines are a class of cognitive-enhancing supplements that are primarily used to treat various symptoms associated with neurological disorders and mental health conditions. These supplements are believed to work by increasing the activity of AMPA receptors in the brain, which help facilitate communication between nerve cells and improve overall brain function.

The origins of ampakines date back to the 1970s, when researchers discovered that certain drug compounds could increase the neuroplasticity of brain cells. Since then, they have been extensively studied for their potential therapeutic benefits in treating a wide range of disorders, including Alzheimer’s disease, ADHD, autism spectrum disorder, and many others.

Today, ampakines are typically prescribed as add-on treatments for these conditions, as well as for general cognitive enhancement. They are generally well tolerated and considered safe when used as directed by a healthcare professional.

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Aniracetam

One of the most popular nootropics for focus and mood
Other Names: Ampamet, Memodrin, Pergamid

Aniracetam is a powerful nootropic supplement that has been used for years to help improve focus, boost memory, and reduce anxiety. Founded in 1970 by a group of scientists at a Swiss pharmaceutical company, Aniracetam was originally developed as an experimental treatment for stroke patients.

Today, this powerful brain booster is commonly used by students and professionals to increase their mental stamina and enhance their cognitive abilities. Some of the most common symptoms that Aniracetam is used for include improving concentration and learning capacity, boosting mood and reducing depression and anxiety, and enhancing memory retention and recall.

Armodafinil

Like Modafinil, but with more of a kick
Other Names: NuVigil, r-modafinil, Waklert, Artvigil, R-Modawake

Armodafinil is a powerful supplement that has been shown to help patients suffering from a wide range of conditions and symptoms, including narcolepsy, shift work sleep disorder, and various other sleeping disorders.

Originating in France in the 1970s, Armodafinil is a unique type of drug that works by targeting and modulating areas of the brain responsible for regulating wakefulness. This helps to promote increased focus and alertness, while also reducing feelings of drowsiness or fatigue.

Despite its relatively recent origins, Armodafinil has quickly become one of the most popular prescription drugs used to manage sleep disorders today. Thanks to its effectiveness and relative safety, it is now commonly prescribed by doctors for patients dealing with everything from depression and anxiety to excessive daytime sleepiness or cognitive impairment.

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Ashwagandha

Traditional herb with potent relaxing effects
Other Names: Withania somnifera, Indian ginsing

Ashwagandha, also known as Indian ginseng, is a popular herbal supplement that is used to treat a variety of different symptoms and conditions. Originally grown in India, this powerful plant has been used for centuries for its many healing properties.

Ashwagandha is especially effective at relieving stress and anxiety, making it a popular choice for those dealing with chronic worry or insomnia. It can also be used to enhance overall mood and energy levels, helping you feel more motivated and focused throughout the day.

In addition to its calming effects, Ashwagandha has been shown to improve immune function, boost cardiovascular health, and even combat the effects of aging by slowing down cell degeneration.

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Bacopa Monnieri

The Indian “Supreme God” herb
Other Names: Brahmi, water hyssop

Bacopa Monnieri is a powerful nootropic supplement that is derived from a plant native to India. Used for centuries by Ayurvedic healers, this herb is prized for its ability to improve memory, enhance focus, and boost overall cognitive function.

Bacopa Monnieri is often used to treat a variety of symptoms related to brain health, including conditions like age-related memory loss, anxiety, depression, and ADHD. In addition to these mental health benefits, this potent herb also has anti-inflammatory and antioxidant properties that can help protect the brain from damage caused by oxidative stress.

BDNF, brain derived neurotrophic factor

BDNF, or brain-derived neurotrophic factor, is a naturally occurring chemical in the body that plays an important role in brain health and function. It is produced by cells in the brain and nervous system, and is believed to be involved in processes related to mood, learning, memory, and stress response.

Many people use BDNF supplements as a way to boost their mental performance and enhance their cognitive health. Some of the symptoms that this supplement is used for include depression, anxiety, memory loss, poor focus, and poor concentration.

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Boron Citrate

Trace element necessary for cognition
Other Names: Borax

Boron citrate is a natural supplement that has been used for centuries to help treat a variety of common health conditions. Originating from the mineral boron, boron citrate is known for its ability to relieve symptoms like joint pain and aches, as well as improve overall mood and energy levels.

In addition, it can also be used to help boost the immune system and enhance mental focus and clarity.

CBD

Non-Psychoactive Cannabis
Other Names: cannabidiol

CBD, short for cannabidiol, is a natural compound found in the cannabis plant that has been used for centuries to relieve a wide variety of symptoms. Its origins can be traced back to ancient India and China, where it was used as an herbal remedy for everything from pain and inflammation to anxiety and depression.

Today, CBD is widely used to treat a multitude of conditions, including chronic pain, insomnia, headaches, and cancer. It has become especially popular in recent years as an alternative treatment option for those who wish to avoid the harmful side effects of traditional medications. Additionally, many people use CBD as a way to promote overall wellness and enhance their physical and mental well-being.

Celastrus Paniculatus

Ayurveda’s Intellect Tree
Other Names: Celastrus oil, Malkangni extract, Jyotishmati, Black oil plant, the intellect tree

Celastrus Paniculatus is a powerful botanical supplement that has been used for centuries to treat a variety of different ailments. This potent plant originates from India, and has been used in traditional Indian medicine as a treatment for everything from insomnia and anxiety to joint pain and digestive issues.

Celastrus Paniculatus is commonly used as a natural alternative to conventional medications, thanks to its wide range of potent healing properties. People use this powerful herb to treat everything from inflammation and headaches to chronic pain and even conditions like depression.

Additionally, this supplement is believed to be an excellent source of antioxidants, which help protect the body against harmful free radicals.

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Centrophenoxine

Synthetic ant-aging compound
Other Names: Lucidril, Centrophenoxin, Cerutil, Helfergin, meclofenoxate

Centrophenoxine is a popular dietary supplement that is used to treat a variety of neurological symptoms, including memory loss, brain fog, and general cognitive decline. This compound was originally developed in 1959 by French scientists who were looking for a way to boost acetylcholine levels in the brain.

Acetylcholine is an important neurotransmitter that plays a critical role in cognitive functioning and memory retention.

Centrophenoxine is widely used by people looking to improve their mental performance and boost focus and concentration levels. This supplement can be taken on its own or combined with other nootropic compounds like racetams or choline supplements. It has also been shown to help protect against age-related cognitive decline, making it a popular choice among older adults looking to maintain their mental sharpness as they grow older.

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Chaga Mushrooms

One of the most powerful antioxidants on Earth
Other Names: Inonotus obliquus

Chaga mushrooms are a natural superfood that is believed to have originated in the northern regions of Russia and Korea. These mushrooms are renowned for their potent healing properties, which are thought to help treat a wide variety of symptoms, including chronic fatigue, digestive problems, and inflammatory conditions.

Known as a “cure-all” supplement, chaga mushrooms have long been used by herbalists and natural health practitioners to promote overall wellness and improve overall vitality. They are typically consumed in tea or tincture form, or added to smoothies or other recipes as an ingredient.

If you’re looking to boost your energy levels, improve your digestion, or relieve pain and inflammation, chaga mushrooms may be just what you need!

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Citicoline

Supercharged source of choline for your brain
Other Names: CDP-choline, cytidine-5-diphosphocholine

Citicoline is a dietary supplement that is derived from a type of oily substance found in the liver and brain. It is commonly used to treat symptoms such as memory loss, confusion, and age-related cognitive decline. Additionally, citicoline has been shown to improve mood, focus, and overall brain health. While research on this supplement is still ongoing, it has been shown to be safe and well-tolerated in most people.

Citicoline was first discovered in the 1950s by Italian researchers who were studying brain chemistry. Since then, it has become widely used as a therapeutic supplement for treating various mental health conditions.

Some of the primary symptoms that citicoline is used to treat include memory loss, cognitive decline, mood disorders like depression or anxiety, and increased focus and concentration.

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Cordyceps Mushroom

The Aphrodesiac Mushroom
Other Names: Cordyceps sinensis, Cordyceps militaris, CS-4

Cordyceps Mushroom is a popular supplement that is widely used for its numerous health benefits. This natural remedy is believed to have originated in China and Tibet, where it has long been used as a traditional herbal medicine to treat a variety of ailments.

Cordyceps mushroom is commonly used to relieve symptoms of respiratory conditions, such as asthma and COPD, as well as boost energy levels and support immune function.

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Delta 8 THC

Delta 8 THC

Hemp that gets you high
Other Names:

Delta 8 THC is a synthetic cannabinoid compound that is derived from the Cannabis sativa plant. This supplement is commonly used to treat a variety of symptoms, including chronic pain, nausea, and anxiety.

Delta 8 THC was first synthesized in the 1970s by researchers who were investigating the effects of cannabinoids on the brain. Since then, it has been widely used for both medical and recreational purposes due to its analgesic and anti-inflammatory properties.

However, unlike Delta 9 THC, which is known to cause psychoactive effects and is therefore illegal in most parts of the US, Delta 8 THC is considered non-psychoactive and can therefore be legally purchased and consumed without restriction.

Dihydroberberine

Most Bio-Available Berberine
Other Names: 7,8-Dihydroberberine,

Dihydroberberine is a plant-based supplement that is commonly used for treating a variety of different symptoms and conditions. Originating from the roots of certain plants, dihydroberberine contains a number of important antioxidants and anti-inflammatory compounds that are thought to promote overall health and well-being.

Some of the most common uses for this supplement include alleviating symptoms associated with high blood pressure, reducing inflammation in the body, preventing nausea, and improving digestive function.

Dihydroberberine may also be useful for improving cardiovascular health, promoting weight loss, and managing pain and discomfort related to certain chronic conditions.

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DLPA

Non-stimulating nootropic for ADHD and mood
Other Names: DL-PHENYLALANINE, phenylalanine

DLPA, or DL-phenylalanine, is a supplement originally developed in the 1960s to treat a range of symptoms and conditions. It is used to ease pain and inflammation associated with conditions like arthritis and fibromyalgia, as well as chronic migraines and other types of headaches.

Other uses include treating chronic fatigue syndrome, depression, anxiety, insomnia, and more. DLPA works by increasing the levels of endorphins in the body, which are natural chemicals that help relieve pain and promote feelings of well-being.

Additionally, DLPA may affect certain receptors in the brain that are involved in regulating mood and emotional states.

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DMAE

Also prescribed under the name Deanol for ADHD
Other Names: dimethylaminoethanol, Deanol

DMAE, or dimethylethanolamine, is a popular dietary supplement that has been used for a variety of therapeutic purposes. Its origins can be traced back to the 1960s, when it was first discovered by researchers studying its effects on the brain.

DMAE is typically used to treat a range of neurological and psychiatric conditions, including ADHD, anxiety, and depression.

Some of the primary benefits of DMAE include improved cognitive function, mood enhancement, and increased energy levels.

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Fl Modafinil

The Off-Label Modafinil
Other Names: CRL 40,940, bisfluoromodafinil, lauflumide

Fl Modafinil is a popular dietary supplement that is used to treat a variety of symptoms and conditions. Its origins can be traced back to the 1970s, when it was first developed as a wakefulness-promoting drug for people suffering from sleep disorders like narcolepsy.

Fl Modafinil is widely used for a range of conditions, including ADHD, depression, and even chronic fatigue syndrome.

Fl Modafinil has been shown to be both safe and effective in treating these conditions by improving mental focus, energy levels, and overall well-being.

It works by boosting levels of several important neurotransmitters in the brain, including dopamine and serotonin. Additionally, this supplement is thought to optimize various biological processes in the body that are essential for health and vitality.

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GABA

Your body’s natural relaxant
Other Names: gamma-aminobutyric acid

GABA, also known as gamma-aminobutyric acid, is a naturally occurring compound in the brain that plays an important role in regulating mood and behavior. It is produced through a series of complex chemical reactions and is thought to be involved in a number of neurological processes, including memory formation, sleep regulation, and anxiety management.

Despite its importance in maintaining normal brain function, GABA supplements have been used for many years as a treatment for various symptoms associated with mental health disorders. Some of the most common symptoms that GABA supplements are used to address include insomnia, stress and anxiety, depression, and hyperactivity. Additionally, they may be taken to help improve focus and cognitive performance in people with attention-deficit disorders like ADHD.

The origins of GABA supplements can be traced back several centuries to traditional herbal remedies used in Ayurvedic medicine.

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Ginkgo Biloba

Ancient herbal cognitive enhancer and energy supplement
Other Names: maidenhair tree

Ginkgo Biloba is a popular herbal supplement that has been used for centuries in traditional Chinese medicine. This supplement is believed to have a wide variety of beneficial effects, including improved memory and cognitive function, reduced anxiety and stress, and relief from symptoms of depression. The main ingredient in Ginkgo Biloba is ginkgo biloba extract, which contains potent antioxidants and other compounds that are thought to boost overall health and wellness.

Sources for this supplement can be traced back to ancient China, where it was traditionally used to treat a number of different conditions.

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Glutamate

Other Names: glutamic acid

Glutamate is a supplement commonly used to treat a variety of symptoms, including mood disorders, pain, and mental health conditions. The origins of this supplement are not entirely clear, though it is believed to have developed as a byproduct of other amino acids in the body.

There are several different types of glutamate available, each with its own set of benefits and uses. Some common forms include L-glutamic acid and monosodium glutamate (MSG), which are typically used to help manage mood disorders like depression and anxiety.

Other forms of glutamate can be used to help alleviate symptoms of chronic pain or reduce inflammation in the body. In addition to these potential benefits, glutamate has also been shown to be effective at improving mental clarity and memory retention.

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Gotu Kola

Medicinal plant used for centuries to support mood and brain health
Other Names: brahmabuti, Centella asiatica, hydrocotyle, Indian pennywort, Indian water navelwort, pennywort

Gotu Kola, also known as centella asiatica, is a plant native to Asia that has been used for centuries in traditional Chinese and Ayurvedic medicine. This herb is commonly taken as a dietary supplement due to its purported ability to treat a variety of symptoms, including anxiety, fatigue, depression, and more.

The origins of gotu kola can be traced back many centuries ago, when it was first used by healers in China and India. In these cultures, it was believed that the herb had powerful healing properties and could be used to treat a wide range of ailments. Today, gotu kola remains a popular supplement found in many natural health stores and online vendors.

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Green Tea Extract

All the benefits of green tea in concentrated form
Other Names: Epigallocatechin gallate (EGCG), epigallocatechin-3-gallate

Green tea extract is a popular dietary supplement, and for good reason. Green tea extract is rich in antioxidants, which have been shown to offer numerous health benefits. These include reducing inflammation, boosting brain function, and protecting against heart disease and cancer. Green tea extract supplements are typically made from the dried leaves of the Camellia sinensis plant.

The leaves are then ground into a powder and concentrated into an extract. This process preserves most of the beneficial compounds in green tea, including polyphenols like epigallocatechin-gallate (EGCG). When it comes to cognitive benefits, green tea extract has been shown to improve memory and reaction time.

One study showed that participants who took green tea extract performed better on a memory test than those who didn’t.

Another study found that green tea extract can help improve reaction time in people with attention deficit hyperactivity disorder (ADHD). The mechanism of action behind these cognitive benefits is not fully understood, but it is thought that the EGCG in green tea extract helps to protect the brain from damage and improve blood flow to the brain.

So, if you’re looking for a natural way to boost your brain power, green tea extract could be worth trying. Just be sure to talk to your doctor first, as green tea supplements can interact with some medications.

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Hordenine

Herbal MAOI
Other Names: N,N-Dimethyltyramine, Anhaline, peyocactine

Hordenine, also known as N,N-dimethyltyramine, is a naturally occurring compound that is found in a number of plants and seeds. It has been traditionally used as a treatment for a variety of symptoms, including fatigue, anxiety, and low mood. Today, hordenine is commonly used as a dietary supplement to improve energy levels and increase mental focus.

The exact origins of hordenine are unknown, but it is thought to occur naturally in various plants and seeds. Some of the most common sources include barley grass, bitter orange peels, and kigelia Africana fruit. It can also be produced synthetically in a lab setting.

One of the main benefits of hordenine is its ability to enhance mental focus and clarity. It works by affecting the levels of certain neurotransmitters in the brain, leading to an overall improvement in cognitive function. Additionally, hordenine is believed to have some mild stimulant effects that may help to boost energy levels and reduce feelings of fatigue or tiredness.

Uses: Alertness, Mood,
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Huperzine A

Traditional Chinese herb for improving cognition
Other Names: Selagine, L-huperzine A

Huperzine A is a supplement that has been used for centuries in traditional Chinese medicine. It is derived from the Chinese club moss plant and has a variety of benefits. Huperzine A works by inhibiting the breakdown of acetylcholine, which is a neurotransmitter that plays a role in memory and learning.

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Huperzine A is available in capsules or tablets. It is important to start with a low dose and gradually increase the dose as tolerated.

L-Glutamine

The most abundant amino acid in your body
Other Names: glutamine, Gln

L-Glutamine is a popular supplement that is believed to help manage a wide range of symptoms, including muscle soreness, fatigue, and brain fog. It is typically derived from dietary sources such as meat and dairy products, though it can also be synthesized in the lab.

The origins of L-Glutamine date back to the early 20th century, when German chemist Hans Adolf Krebs first discovered its ability to help boost energy levels and reduce physical fatigue. Today, many athletes and other active individuals use L-Glutamine as a way to improve their performance and recovery times after strenuous workouts or competitions.

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L-Ornithine

Holistic stamina and stress support
Other Names: ornithine, levo-ornithine

L-Ornithine is a popular supplement that is commonly used for a variety of different health conditions. This supplement is believed to have its origins in ancient Chinese medicine, and it has been used for centuries to treat symptoms like insomnia, anxiety, and stress.

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L-theanine

The all-natural “chill pill”
Other Names: r-glutamylethylamide

L-theanine is a supplement derived from green tea that has been used for many years to treat a variety of symptoms. Its exact origins are unknown, but it is believed to have originated in either China or Japan.

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Powerful medicinal mushroom for brain health
Other Names: Hericium erinaceus, yamabushitake,

Lion’s Mane is a popular supplement that is derived from a type of mushroom called Hericium erinaceus. It has been used for centuries in traditional Chinese medicine to treat a variety of ailments, including memory loss, anxiety, and depression.

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Lithium Orotate

Important trace element with profound mental effects
Other Names: Lithium salt, Li

Lithium orotate is a supplement that is often used to treat symptoms of depression and anxiety, as well as other mental health conditions. The supplement is derived from orotic acid, a natural compound found in many foods and beverages. While the exact origins of lithium orotate are not known, it is thought to have been developed in the 1970s by Dr. Hans Nieper, a German physician and researcher.

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Maitake Mushroom

Other Names: Grifola frondosa, hen of the woods, ram’s head mushroom

Maitake mushroom, also known as hen of the woods, is a type of medicinal mushroom that has been used for centuries in traditional Asian medicine to treat a variety of health conditions. It is believed to have anti-inflammatory and immune-boosting properties, and is often used to help relieve symptoms of conditions like heart disease, high blood pressure, and diabetes.

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Neuroprotective and anti-Alzheimer’s drug
Other Names: Namenda

Memantine is a drug that is used primarily to treat symptoms of Alzheimer’s disease and other neurodegenerative disorders. It was originally developed in the 1960s by a German pharmaceutical company, and was designed to target glutamate receptors in the brain.

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Methylene Blue

Other Names:

Methylene Blue is a potent supplement that has been used for centuries to treat a variety of symptoms. Originally developed as an anti-malarial drug, it was later found to be effective in treating other conditions and disorders.

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Natural dopamine
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Mucuna pruriens, also known as velvet bean, is a plant native to Africa and Asia that has been used for thousands of years as a medicinal supplement. It is typically taken to treat a variety of symptoms, including anxiety and depression, low energy levels, sexual dysfunction, and more.

The origins of Mucuna pruriens can be traced back across many different cultures and traditions. It has long been used in Ayurvedic medicine in India, where it was esteemed for its ability to increase energy levels and improve overall health. Today, it is commonly used all around the world as a natural remedy for a range of conditions.

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Versatile and effective all-round cognitive supplement
Other Names: N-acetylcysteine, Acetylcysteine, Acetadote, Fluimucil, Mucomyst

NAC, or n-acetyl cysteine, is a supplement that is used to treat a variety of different symptoms and conditions. It is believed to have its origins in the 1960s, when research first began to explore its possible benefits for preventing and treating respiratory tract infections like bronchitis and pneumonia.

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Effective, natural way to support dopamine
Other Names: N-Acetyl-L-tyrosine, Tyrosine, NALT

NALT, or N-acetyl-L-tyrosine, is a dietary supplement that is commonly used to address a number of different symptoms and conditions. The origins of this supplement date back to the 1960s, when it was first developed as a pharmaceutical treatment for Parkinson’s disease. Since then, it has been used to help boost energy levels, improve mood and cognitive function, and ease stress and anxiety.

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Not just for smokers anymore
Other Names: 3-(1-Methyl-2-pyrrolidinyl) pyridine

Nicotine is a natural compound that is found in the leaves of certain plants, including tobacco. It is typically used as a supplement to help people manage symptoms like anxiety and depression, as well as to promote focus and concentration.

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World’s #1 selling nootropic (and for good reason)
Other Names: n-phenylacetyl-l-prolylglycine ethyl ester

Noopept is a powerful nootropic supplement that was originally developed in Russia as a treatment for cognitive disorders like Alzheimer’s disease and dementia.

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Herbal nerve tonic
Other Names: Wild green oats

Oat straw supplements are a popular herbal remedy made from the dried stems and leaves of the oat plant. They have been used for centuries to treat a variety of ailments, including anxiety, insomnia, and fatigue.

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Extremely popular synthetic learning and memory aid
Other Names:

Oxiracetam is a nootropic supplement that has been used for many years to help improve memory, learning, and focus. It was originally developed in the 1970s by a team of Hungarian scientists, and was initially used as a treatment for Alzheimer’s disease. However, it quickly became popular among the general public due to its ability to enhance cognitive function and increase productivity.

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Extremely powerful anti-anxiety drug developed by the Soviet space agency
Other Names: Fenibut, 4-Amino-3-phenylbutanoic acid, Phenylgamma

Phenibut is a powerful nootropic supplement that has origins in the Soviet Union. It is believed to help improve cognitive function and boost mental clarity, making it popular among students and professionals who need to stay focused and productive for long periods of time.
Phenibut is a powerful nootropic supplement that has origins in the Soviet Union.

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Closest legal alternative to Adderall
Other Names: Fonturacetam, Carphedon, 4-Phenyl-2-pyrrolidone-1-acetamide

Phenylpiracetam is a powerful nootropic supplement that was originally developed in Russia as a way to improve focus and concentration, reduce fatigue, and enhance physical stamina.

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Crucial component of all neural cells
Other Names: PC

Phosphatidylcholine, also known as PC, is a type of phospholipid that is found in the cells of many different types of organisms. This supplement is believed to offer several health benefits, including improved cognitive function, reduced cholesterol levels, and reduced symptoms of anxiety and depression.

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Critical building block of your braincells
Other Names: PS, PS Sharp

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A safer potential alternative to Xanax
Other Names: pycamilon, pikamilon, nicotinoyl-GABA

Picamilon is a dietary supplement that is commonly used to treat a variety of symptoms and conditions, including anxiety, stress, depression, and insomnia. It was originally developed in the Soviet Union in 1969, and its use has since spread throughout Europe and the United States.

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All natural ADHD remedy
Other Names: Proanthocyanidins, Pine Bark Maritime Extract, Pycnogenol®

Pine bark extract is a powerful nutritional supplement that has been used for centuries in traditional Chinese medicine. This extract is derived from the pine needles and bark of certain pine trees and is known for its high antioxidant content.

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Piracetam

The original nootropic
Other Names: Nootropil, Lucetam, Biotropil, Stimulan, Breinox

Piracetam is a popular nootropic supplement that has been used for many years to help improve cognitive function, memory, and focus. It is believed to have originated in the 1960s, when researchers first discovered its ability to enhance brain activity.

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A more potent version of the original piracetam
Other Names: Pramistar

Pramiracetam is a nootropic supplement that has been used for many years to treat a variety of cognitive and neurological symptoms. Its origins can be traced back to the 1970s, when it was developed by the pharmaceutical company Parke-Davis as an experimental drug.

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Memory enancer
Other Names: Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate

PRL-8-53 is a dietary supplement that was originally developed in the 1970s by researchers at the University of Rhodesia, now known as Zimbabwe. It has been used for a variety of purposes, including enhancing memory and cognitive function, reducing stress and anxiety, and improving sleep quality.

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Powerful Mitochondria Booster
Other Names: pyrroloquinoline quinone, PQQ, methoxatin, Coenzyme pqq

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A staple in Eastern medicine
Other Names: Lingzhi, Ganoderma lucidum, Jong Siryongji, Mannentake

Reishi mushroom, also known as lingzhi mushroom, is a medicinal fungus traditionally used in Chinese medicine to treat a variety of ailments. This powerful natural remedy is believed to have anti-inflammatory, antiviral, and immune-boosting properties, making it highly effective for treating everything from respiratory infections and chronic fatigue to high blood pressure and anxiety.

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Ancient herbal performance enhancer
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Saffron

Other Names: Crocus sativus

Saffron is a popular herbal supplement that has been used for centuries as a remedy for various health conditions. Originally native to the Mediterranean region, saffron is now also cultivated in other parts of the world, including Asia and North America.

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Prescription drug for Alzheimer’s and neuroprotection
Other Names: N-methylglycine

Sarcosine, also known as N-methylglycine, is a naturally occurring amino acid that is produced by the human body. It has been used in supplement form to help treat a number of different symptoms, including depression, schizophrenia, and drug addiction. Some research has also suggested that it may be useful in promoting weight loss and improving cognition.

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A neuroprotectant also prescribed under the name Deprenyl
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Highly stimulating vitamin B derivative
Other Names: Arcalion

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Not just for energy drinks
Other Names: Aminoethylsulfonic acid, Taurineold

Taurine is a popular supplement that has origins in both traditional Chinese medicine and modern scientific research. While it is primarily known for its ability to reduce symptoms of anxiety and insomnia, it is also used to support the health of the cardiovascular system, boost energy levels, and improve overall cognitive function. Additionally, many people take taurine supplements for their antioxidant properties, as well as for their potential benefits for muscle growth and recovery.

The exact mechanisms by which taurine works are not fully understood by scientists, but it is believed to influence various chemical signaling pathways in the brain. Taurine supplements can be found online or at most health and nutrition stores, and they are generally considered safe when used appropriately. However, they may interact with certain medications or medical conditions, so it is always advisable to speak with your doctor before beginning any new supplement regimen.

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Theacrine

Coffee alternative extracted from the tea plant
Other Names: TeaCrineTM, 1,3,7,9-tetramethyluric acid

Theacrine is a natural supplement that is believed to help improve mood, focus, and energy levels. It is believed to have its origins in China, where it was traditionally used in tea as an energizing beverage.

Today, theacrine is used primarily as a nootropic supplement, and is often taken to help alleviate symptoms of fatigue or low mood. Some people also use it to help enhance mental clarity or focus, making it a popular supplement among students and other busy professionals. Additionally, some users claim that theacrine can help improve athletic performance by reducing feelings of pain or discomfort during physical activity.

Overall, theacrine is considered a safe and effective supplement with a wide range of possible benefits for those looking to boost their physical and mental well-being.

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Uridine Monophosphate

One of the basic building blocks of your body
Other Names: UMP, Uridine Monophosphate

Uridine Monophosphate, or UMP, is a popular dietary supplement that has gained popularity in recent years for its purported benefits to brain health. While the origins of UMP are not entirely clear, it is believed to have originated from the natural chemical uridine, which is found in many foods and can also be produced synthetically.

UMP is used for a variety of different symptoms, including improving mental performance and memory, increasing focus and concentration, and protecting against cognitive decline associated with aging.

It has also been shown to help improve symptoms related to mood disorders like depression and anxiety. Overall, UMP is considered a safe and effective supplement that may help promote overall brain health and wellness.

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Vinpocetine

Cognitive enhancement and neuroprotective found in the periwinkle plant
Other Names: Cavinton, Ethyl Apovincaminate

Vinpocetine is a dietary supplement that is often used to treat a variety of medical conditions, including memory loss, stroke, and certain types of dementia. This supplement is believed to work by increasing blood flow to the brain and enhancing various chemical pathways in the brain that are critical for memory and cognition.

Vinpocetine was first developed in Hungary in the 1970s and has been used as a treatment for neurological disorders ever since. Today, it is commonly prescribed by doctors to help treat conditions like Alzheimer’s disease, Parkinson’s disease, and other forms of cognitive impairment.

In addition to these medical applications, some people also take Vinpocetine to improve their cognitive performance and enhance their mental function. This makes it popular among students who need extra focus and concentration, as well as those who want to keep their minds sharp as they age.

Overall, Vinpocetine is an effective supplement that shows great promise for the treatment of neurological disorders and improved brain health. If you are looking for an effective way to boost your cognitive performance or help prevent age-related memory loss, then this supplement may be right for you.