Nootropics Glossary

A Comprehensive List of Nootropics, Mind-Boosting Supplements, and Drugs

Nootropics, sometimes called “smart drugs,” are substances that are claimed to improve cognitive function. Nootropics are becoming an increasingly popular way to boost mental performance, and there is a wide variety of different substances that fall into this category.

This comprehensive list will outline all of the most important nootropics, including their key benefits and side effects. If you’re looking to give your mind an extra edge, then read on!

5-HTP

Safe and effective serotonin support for mood and sleep
Other Names: 5-Hydroxytryptophan

Acetyl L-Carnitine (ALCAR)

The Red Meat Amino
Other Names: ALCAR, L-Carnitine, Acetyl L-Carnitine

Acetyl L-Carnitine, also known simply as ALCAR, is a naturally occurring amino acid that is commonly used as a dietary supplement. Originating from animal sources like beef and milk, this compound has long been used in traditional medicine to help treat various symptoms and conditions. Today, it is widely used for a variety of purposes, including promoting heart health, boosting energy levels, and improving cognitive function.

Some of the main benefits of ALCAR supplementation include increased metabolism, increased insulin sensitivity, reduced fatigue and muscle soreness after workouts, and improved memory and focus. Additionally, because this compound is thought to have anti-aging properties, it has become popular among those looking to improve their overall health and wellbeing over time.

Overall, if you are looking for a safe and effective way to boost your health and wellbeing through natural means, then ALCAR may be a good option for you. However, it is always important to consult with a healthcare professional before beginning any new supplement regimen.

Adrafinil

A legal over-the-counter version on Modafinil
Other Names: Olmifon

Adrafinil is a popular nootropic supplement that was originally developed in France in the 1970s as a treatment for narcolepsy. It works by increasing levels of several neurochemicals in the brain, including dopamine, norepinephrine, and serotonin. This helps to boost mental clarity and focus, as well as relieve symptoms of depression and anxiety.

Adrafinil is often used by people who want to improve their concentration and cognitive function, especially those suffering from age-related cognitive decline or disorders like ADHD or dementia. It is also commonly used as a study aid or to enhance athletic performance, due to its ability to improve energy levels and reduce fatigue.

In addition to these benefits, Adrafinil may also be used to treat certain sleep disorders such as REM behavior disorder or obstructive sleep apnea. While it has not been approved by the FDA for any medical purposes, it is generally considered safe when taken in recommended dosages. However, it should not be taken by individuals with liver disease or high blood pressure.

Alpha-GPC

Great source of choline that works well in nootropic stacks
Other Names: L-Alpha glycerylphosphorylcholine, Choline Alfoscerate

Alpha-GPC, or alpha-glycerophosphocholine, is a supplement that is commonly used to treat a variety of symptoms and conditions. It is believed to have many beneficial effects on the body, including improving memory and focus, enhancing athletic performance, and reducing the risk of age-related health conditions like dementia and Alzheimer’s disease.

The origins of Alpha-GPC can be traced back to Europe in the 1950s, when it was first developed as a way to treat patients with neurological disorders like stroke and traumatic brain injury. Since then, its potential benefits have been investigated in numerous clinical trials and studies. Today, Alpha-GPC is typically marketed as a nootropic supplement used by both healthy individuals and those suffering from various cognitive conditions.

Some of the most common symptoms that Alpha-GPC is used for include memory loss, cognitive decline, attention deficit disorders (ADD/ADHD), depression, anxiety, and chronic fatigue syndrome. However, its effectiveness for these conditions remains unclear due to conflicting results from studies. Overall, more research into the benefits and safety of Alpha-GPC is needed in order to better understand its role in treating various health conditions.

Ampakines

Extremely potent synthetic nootropic
Other Names: CX compounds

Ampakines are a class of cognitive-enhancing supplements that are primarily used to treat various symptoms associated with neurological disorders and mental health conditions. These supplements are believed to work by increasing the activity of AMPA receptors in the brain, which help facilitate communication between nerve cells and improve overall brain function.

The origins of ampakines date back to the 1970s, when researchers discovered that certain drug compounds could increase the neuroplasticity of brain cells. Since then, they have been extensively studied for their potential therapeutic benefits in treating a wide range of disorders, including Alzheimer’s disease, ADHD, autism spectrum disorder, and many others.

Today, ampakines are typically prescribed as add-on treatments for these conditions, as well as for general cognitive enhancement. They are generally well tolerated and considered safe when used as directed by a healthcare professional.

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Aniracetam

One of the most popular nootropics for focus and mood
Other Names: Ampamet, Memodrin, Pergamid

Aniracetam is a powerful nootropic supplement that has been used for years to help improve focus, boost memory, and reduce anxiety. Founded in 1970 by a group of scientists at a Swiss pharmaceutical company, Aniracetam was originally developed as an experimental treatment for stroke patients.

Today, this powerful brain booster is commonly used by students and professionals to increase their mental stamina and enhance their cognitive abilities. Some of the most common symptoms that Aniracetam is used for include improving concentration and learning capacity, boosting mood and reducing depression and anxiety, and enhancing memory retention and recall.

Armodafinil

Like Modafinil, but with more of a kick
Other Names: NuVigil, r-modafinil, Waklert, Artvigil, R-Modawake

Armodafinil is a powerful supplement that has been shown to help patients suffering from a wide range of conditions and symptoms, including narcolepsy, shift work sleep disorder, and various other sleeping disorders.

Originating in France in the 1970s, Armodafinil is a unique type of drug that works by targeting and modulating areas of the brain responsible for regulating wakefulness. This helps to promote increased focus and alertness, while also reducing feelings of drowsiness or fatigue.

Despite its relatively recent origins, Armodafinil has quickly become one of the most popular prescription drugs used to manage sleep disorders today. Thanks to its effectiveness and relative safety, it is now commonly prescribed by doctors for patients dealing with everything from depression and anxiety to excessive daytime sleepiness or cognitive impairment.

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Ashwagandha

Traditional herb with potent relaxing effects
Other Names: Withania somnifera, Indian ginsing

Ashwagandha, also known as Indian ginseng, is a popular herbal supplement that is used to treat a variety of different symptoms and conditions. Originally grown in India, this powerful plant has been used for centuries for its many healing properties.

Ashwagandha is especially effective at relieving stress and anxiety, making it a popular choice for those dealing with chronic worry or insomnia. It can also be used to enhance overall mood and energy levels, helping you feel more motivated and focused throughout the day.

In addition to its calming effects, Ashwagandha has been shown to improve immune function, boost cardiovascular health, and even combat the effects of aging by slowing down cell degeneration.

Bacopa Monnieri

The Indian “Supreme God” herb
Other Names: Brahmi, water hyssop

Bacopa Monnieri is a powerful nootropic supplement that is derived from a plant native to India. Used for centuries by Ayurvedic healers, this herb is prized for its ability to improve memory, enhance focus, and boost overall cognitive function.

Bacopa Monnieri is often used to treat a variety of symptoms related to brain health, including conditions like age-related memory loss, anxiety, depression, and ADHD. In addition to these mental health benefits, this potent herb also has anti-inflammatory and antioxidant properties that can help protect the brain from damage caused by oxidative stress.

BDNF, or brain-derived neurotrophic factor, is a naturally occurring chemical in the body that plays an important role in brain health and function. It is produced by cells in the brain and nervous system, and is believed to be involved in processes related to mood, learning, memory, and stress response.

Many people use BDNF supplements as a way to boost their mental performance and enhance their cognitive health. Some of the symptoms that this supplement is used for include depression, anxiety, memory loss, poor focus, and poor concentration.

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Boron Citrate

Trace element necessary for cognition
Other Names: Borax

Boron citrate is a natural supplement that has been used for centuries to help treat a variety of common health conditions. Originating from the mineral boron, boron citrate is known for its ability to relieve symptoms like joint pain and aches, as well as improve overall mood and energy levels.

In addition, it can also be used to help boost the immune system and enhance mental focus and clarity.

CBD

Non-Psychoactive Cannabis
Other Names: cannabidiol

CBD, short for cannabidiol, is a natural compound found in the cannabis plant that has been used for centuries to relieve a wide variety of symptoms. Its origins can be traced back to ancient India and China, where it was used as an herbal remedy for everything from pain and inflammation to anxiety and depression.

Today, CBD is widely used to treat a multitude of conditions, including chronic pain, insomnia, headaches, and cancer. It has become especially popular in recent years as an alternative treatment option for those who wish to avoid the harmful side effects of traditional medications. Additionally, many people use CBD as a way to promote overall wellness and enhance their physical and mental well-being.

Celastrus Paniculatus

Ayurveda’s Intellect Tree
Other Names: Celastrus oil, Malkangni extract, Jyotishmati, Black oil plant, the intellect tree

Celastrus Paniculatus is a powerful botanical supplement that has been used for centuries to treat a variety of different ailments. This potent plant originates from India, and has been used in traditional Indian medicine as a treatment for everything from insomnia and anxiety to joint pain and digestive issues.

Celastrus Paniculatus is commonly used as a natural alternative to conventional medications, thanks to its wide range of potent healing properties. People use this powerful herb to treat everything from inflammation and headaches to chronic pain and even conditions like depression.

Additionally, this supplement is believed to be an excellent source of antioxidants, which help protect the body against harmful free radicals.

Centrophenoxine

Synthetic ant-aging compound
Other Names: Lucidril, Centrophenoxin, Cerutil, Helfergin, meclofenoxate

Centrophenoxine is a popular dietary supplement that is used to treat a variety of neurological symptoms, including memory loss, brain fog, and general cognitive decline. This compound was originally developed in 1959 by French scientists who were looking for a way to boost acetylcholine levels in the brain.

Acetylcholine is an important neurotransmitter that plays a critical role in cognitive functioning and memory retention.

Centrophenoxine is widely used by people looking to improve their mental performance and boost focus and concentration levels. This supplement can be taken on its own or combined with other nootropic compounds like racetams or choline supplements. It has also been shown to help protect against age-related cognitive decline, making it a popular choice among older adults looking to maintain their mental sharpness as they grow older.

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Chaga Mushrooms

One of the most powerful antioxidants on Earth
Other Names: Inonotus obliquus

Chaga mushrooms are a natural superfood that is believed to have originated in the northern regions of Russia and Korea. These mushrooms are renowned for their potent healing properties, which are thought to help treat a wide variety of symptoms, including chronic fatigue, digestive problems, and inflammatory conditions.

Known as a “cure-all” supplement, chaga mushrooms have long been used by herbalists and natural health practitioners to promote overall wellness and improve overall vitality. They are typically consumed in tea or tincture form, or added to smoothies or other recipes as an ingredient.

If you’re looking to boost your energy levels, improve your digestion, or relieve pain and inflammation, chaga mushrooms may be just what you need!

Citicoline

Supercharged source of choline for your brain
Other Names: CDP-choline, cytidine-5-diphosphocholine

Citicoline is a dietary supplement that is derived from a type of oily substance found in the liver and brain. It is commonly used to treat symptoms such as memory loss, confusion, and age-related cognitive decline. Additionally, citicoline has been shown to improve mood, focus, and overall brain health. While research on this supplement is still ongoing, it has been shown to be safe and well-tolerated in most people.

Citicoline was first discovered in the 1950s by Italian researchers who were studying brain chemistry. Since then, it has become widely used as a therapeutic supplement for treating various mental health conditions.

Some of the primary symptoms that citicoline is used to treat include memory loss, cognitive decline, mood disorders like depression or anxiety, and increased focus and concentration.

Cordyceps Mushroom

The Aphrodesiac Mushroom
Other Names: Cordyceps sinensis, Cordyceps militaris, CS-4

Cordyceps Mushroom is a popular supplement that is widely used for its numerous health benefits. This natural remedy is believed to have originated in China and Tibet, where it has long been used as a traditional herbal medicine to treat a variety of ailments.

Cordyceps mushroom is commonly used to relieve symptoms of respiratory conditions, such as asthma and COPD, as well as boost energy levels and support immune function.

It may also be prescribed to help treat fatigue, high blood pressure, chronic inflammation, and other conditions.

Delta 8 THC

Hemp that gets you high
Other Names:

Delta 8 THC is a synthetic cannabinoid compound that is derived from the Cannabis sativa plant. This supplement is commonly used to treat a variety of symptoms, including chronic pain, nausea, and anxiety.

Delta 8 THC was first synthesized in the 1970s by researchers who were investigating the effects of cannabinoids on the brain. Since then, it has been widely used for both medical and recreational purposes due to its analgesic and anti-inflammatory properties.

However, unlike Delta 9 THC, which is known to cause psychoactive effects and is therefore illegal in most parts of the US, Delta 8 THC is considered non-psychoactive and can therefore be legally purchased and consumed without restriction.

Dihydroberberine

Most Bio-Available Berberine
Other Names: 7,8-Dihydroberberine,

Dihydroberberine is a plant-based supplement that is commonly used for treating a variety of different symptoms and conditions. Originating from the roots of certain plants, dihydroberberine contains a number of important antioxidants and anti-inflammatory compounds that are thought to promote overall health and well-being.

Some of the most common uses for this supplement include alleviating symptoms associated with high blood pressure, reducing inflammation in the body, preventing nausea, and improving digestive function.

Dihydroberberine may also be useful for improving cardiovascular health, promoting weight loss, and managing pain and discomfort related to certain chronic conditions.

DLPA

Non-stimulating nootropic for ADHD and mood
Other Names: DL-PHENYLALANINE, phenylalanine

DLPA, or DL-phenylalanine, is a supplement originally developed in the 1960s to treat a range of symptoms and conditions. It is used to ease pain and inflammation associated with conditions like arthritis and fibromyalgia, as well as chronic migraines and other types of headaches.

Other uses include treating chronic fatigue syndrome, depression, anxiety, insomnia, and more. DLPA works by increasing the levels of endorphins in the body, which are natural chemicals that help relieve pain and promote feelings of well-being.

Additionally, DLPA may affect certain receptors in the brain that are involved in regulating mood and emotional states.

DMAE

Also prescribed under the name Deanol for ADHD
Other Names: dimethylaminoethanol, Deanol

DMAE, or dimethylethanolamine, is a popular dietary supplement that has been used for a variety of therapeutic purposes. Its origins can be traced back to the 1960s, when it was first discovered by researchers studying its effects on the brain.

DMAE is typically used to treat a range of neurological and psychiatric conditions, including ADHD, anxiety, and depression.

Some of the primary benefits of DMAE include improved cognitive function, mood enhancement, and increased energy levels.

This supplement is also believed to help boost focus and concentration as well as lower inflammation in the body. Additionally, some people take DMAE in order to increase muscle tone and promote weight loss.

Stacks Well With: Methylene Blue

Fl Modafinil

The Off-Label Modafinil
Other Names: CRL 40,940, bisfluoromodafinil, lauflumide

Fl Modafinil is a popular dietary supplement that is used to treat a variety of symptoms and conditions. Its origins can be traced back to the 1970s, when it was first developed as a wakefulness-promoting drug for people suffering from sleep disorders like narcolepsy.

Fl Modafinil is widely used for a range of conditions, including ADHD, depression, and even chronic fatigue syndrome.

Fl Modafinil has been shown to be both safe and effective in treating these conditions by improving mental focus, energy levels, and overall well-being.

It works by boosting levels of several important neurotransmitters in the brain, including dopamine and serotonin. Additionally, this supplement is thought to optimize various biological processes in the body that are essential for health and vitality.

GABA

Your body’s natural relaxant
Other Names: gamma-aminobutyric acid

GABA, also known as gamma-aminobutyric acid, is a naturally occurring compound in the brain that plays an important role in regulating mood and behavior. It is produced through a series of complex chemical reactions and is thought to be involved in a number of neurological processes, including memory formation, sleep regulation, and anxiety management.

Despite its importance in maintaining normal brain function, GABA supplements have been used for many years as a treatment for various symptoms associated with mental health disorders. Some of the most common symptoms that GABA supplements are used to address include insomnia, stress and anxiety, depression, and hyperactivity. Additionally, they may be taken to help improve focus and cognitive performance in people with attention-deficit disorders like ADHD.

The origins of GABA supplements can be traced back several centuries to traditional herbal remedies used in Ayurvedic medicine.

Ginkgo Biloba

Ancient herbal cognitive enhancer and energy supplement
Other Names: maidenhair tree

Ginkgo Biloba is a popular herbal supplement that has been used for centuries in traditional Chinese medicine. This supplement is believed to have a wide variety of beneficial effects, including improved memory and cognitive function, reduced anxiety and stress, and relief from symptoms of depression. The main ingredient in Ginkgo Biloba is ginkgo biloba extract, which contains potent antioxidants and other compounds that are thought to boost overall health and wellness.

Sources for this supplement can be traced back to ancient China, where it was traditionally used to treat a number of different conditions.

Today, Ginkgo Biloba is most commonly used as a treatment for memory-related disorders like Alzheimer’s disease and dementia. It is also frequently taken as a general wellness supplement for people looking for improved mental clarity and energy levels. Additionally, some people use Ginkgo Biloba to manage the symptoms of depression or anxiety.

Glutamate

Other Names: glutamic acid

Glutamate is a supplement commonly used to treat a variety of symptoms, including mood disorders, pain, and mental health conditions. The origins of this supplement are not entirely clear, though it is believed to have developed as a byproduct of other amino acids in the body.

There are several different types of glutamate available, each with its own set of benefits and uses. Some common forms include L-glutamic acid and monosodium glutamate (MSG), which are typically used to help manage mood disorders like depression and anxiety.

Other forms of glutamate can be used to help alleviate symptoms of chronic pain or reduce inflammation in the body. In addition to these potential benefits, glutamate has also been shown to be effective at improving mental clarity and memory retention.

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Gotu Kola

Medicinal plant used for centuries to support mood and brain health
Other Names: brahmabuti, Centella asiatica, hydrocotyle, Indian pennywort, Indian water navelwort, pennywort

Gotu Kola, also known as centella asiatica, is a plant native to Asia that has been used for centuries in traditional Chinese and Ayurvedic medicine. This herb is commonly taken as a dietary supplement due to its purported ability to treat a variety of symptoms, including anxiety, fatigue, depression, and more.

The origins of gotu kola can be traced back many centuries ago, when it was first used by healers in China and India. In these cultures, it was believed that the herb had powerful healing properties and could be used to treat a wide range of ailments. Today, gotu kola remains a popular supplement found in many natural health stores and online vendors.

While the exact mechanisms behind its purported benefits are not fully understood, there is some evidence to suggest that this plant may help relieve certain symptoms by influencing the production of certain chemicals in the brain. Additionally, some research has shown that gotu kola may have antioxidant and anti-inflammatory properties that help protect against degenerative diseases like Alzheimer’s disease or Parkinson’s disease.

Green Tea Extract

All the benefits of green tea in concentrated form
Other Names: Epigallocatechin gallate (EGCG), epigallocatechin-3-gallate

Green tea extract is a popular dietary supplement, and for good reason. Green tea extract is rich in antioxidants, which have been shown to offer numerous health benefits. These include reducing inflammation, boosting brain function, and protecting against heart disease and cancer. Green tea extract supplements are typically made from the dried leaves of the Camellia sinensis plant.

The leaves are then ground into a powder and concentrated into an extract. This process preserves most of the beneficial compounds in green tea, including polyphenols like epigallocatechin-gallate (EGCG). When it comes to cognitive benefits, green tea extract has been shown to improve memory and reaction time.

One study showed that participants who took green tea extract performed better on a memory test than those who didn’t.

Another study found that green tea extract can help improve reaction time in people with attention deficit hyperactivity disorder (ADHD). The mechanism of action behind these cognitive benefits is not fully understood, but it is thought that the EGCG in green tea extract helps to protect the brain from damage and improve blood flow to the brain.

So, if you’re looking for a natural way to boost your brain power, green tea extract could be worth trying. Just be sure to talk to your doctor first, as green tea supplements can interact with some medications.

Hordenine

Herbal MAOI
Other Names: N,N-Dimethyltyramine, Anhaline, peyocactine

Hordenine, also known as N,N-dimethyltyramine, is a naturally occurring compound that is found in a number of plants and seeds. It has been traditionally used as a treatment for a variety of symptoms, including fatigue, anxiety, and low mood. Today, hordenine is commonly used as a dietary supplement to improve energy levels and increase mental focus.

The exact origins of hordenine are unknown, but it is thought to occur naturally in various plants and seeds. Some of the most common sources include barley grass, bitter orange peels, and kigelia Africana fruit. It can also be produced synthetically in a lab setting.

One of the main benefits of hordenine is its ability to enhance mental focus and clarity. It works by affecting the levels of certain neurotransmitters in the brain, leading to an overall improvement in cognitive function. Additionally, hordenine is believed to have some mild stimulant effects that may help to boost energy levels and reduce feelings of fatigue or tiredness.

Uses: Alertness, Mood,
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Huperzine A

Traditional Chinese herb for improving cognition
Other Names: Selagine, L-huperzine A

Huperzine A is a supplement that has been used for centuries in traditional Chinese medicine. It is derived from the Chinese club moss plant and has a variety of benefits. Huperzine A works by inhibiting the breakdown of acetylcholine, which is a neurotransmitter that plays a role in memory and learning.

This can lead to improved cognitive function and memory. Huperzine A is also an antioxidant and has anti-inflammatory properties. It has been shown to be effective in treating Alzheimer’s disease, dementia, and age-related cognitive decline.

Huperzine A is available in capsules or tablets. It is important to start with a low dose and gradually increase the dose as tolerated.

L-Glutamine

The most abundant amino acid in your body
Other Names: glutamine, Gln

L-Glutamine is a popular supplement that is believed to help manage a wide range of symptoms, including muscle soreness, fatigue, and brain fog. It is typically derived from dietary sources such as meat and dairy products, though it can also be synthesized in the lab.

The origins of L-Glutamine date back to the early 20th century, when German chemist Hans Adolf Krebs first discovered its ability to help boost energy levels and reduce physical fatigue. Today, many athletes and other active individuals use L-Glutamine as a way to improve their performance and recovery times after strenuous workouts or competitions.

Other potential uses for L-Glutamine include improving gut health and supporting brain function. Some people also take it to help prevent or manage certain mental health conditions like anxiety or depression.

L-Ornithine

Holistic stamina and stress support
Other Names: ornithine, levo-ornithine

L-Ornithine is a popular supplement that is commonly used for a variety of different health conditions. This supplement is believed to have its origins in ancient Chinese medicine, and it has been used for centuries to treat symptoms like insomnia, anxiety, and stress.

Today, L-Ornithine is typically used as a natural remedy for these and other ailments, as well as to promote overall health and wellbeing. Some of the most common uses of this supplement include improving mental focus and alertness, boosting energy levels, and reducing inflammation throughout the body.

Additionally, it may help to support weight loss efforts by suppressing appetite and increasing feelings of fullness after meals.

L-theanine

The all-natural “chill pill”
Other Names: r-glutamylethylamide

L-theanine is a supplement derived from green tea that has been used for many years to treat a variety of symptoms. Its exact origins are unknown, but it is believed to have originated in either China or Japan.

L-theanine is primarily used to treat anxiety and stress, though it is also often used as a sleep aid and to reduce heart rate. It works by affecting certain chemicals in the brain that help regulate mood and behavior, resulting in a calming effect that can relieve symptoms of anxiety and stress.

While L-theanine may not be appropriate for everyone, it can be an effective treatment option for those who suffer from mild to moderate forms of these conditions.

Lion’s Mane

Powerful medicinal mushroom for brain health
Other Names: Hericium erinaceus, yamabushitake,

Lion’s Mane is a popular supplement that is derived from a type of mushroom called Hericium erinaceus. It has been used for centuries in traditional Chinese medicine to treat a variety of ailments, including memory loss, anxiety, and depression.

Today, it is commonly taken as a natural nootropic to boost cognitive function and support overall brain health.

Some of the potential benefits of Lion’s Mane supplementation include improved focus and concentration, enhanced memory and learning ability, reduced anxiety and stress levels, and protection against age-related mental decline. It also appears to have anti-inflammatory properties that can help reduce symptoms associated with conditions like arthritis and IBS.

Overall, this powerful supplement shows great potential for supporting overall wellness and mental health.

Lithium Orotate

Important trace element with profound mental effects
Other Names: Lithium salt, Li

Lithium orotate is a supplement that is often used to treat symptoms of depression and anxiety, as well as other mental health conditions. The supplement is derived from orotic acid, a natural compound found in many foods and beverages. While the exact origins of lithium orotate are not known, it is thought to have been developed in the 1970s by Dr. Hans Nieper, a German physician and researcher.

Today, lithium orotate is often prescribed by medical professionals as a treatment for conditions like bipolar disorder and depression. It is also sometimes used as an adjunctive therapy alongside other prescription medications in order to enhance their effects or reduce side effects. Some people use lithium orotate on their own to help manage milder forms of depression and anxiety, or simply to improve overall mood and energy levels.

Overall, lithium orotate is an effective treatment for many common mental health conditions, though it should always be taken under the supervision of a medical professional. If you are considering using this supplement to manage your symptoms, be sure to discuss all potential risks and benefits with your doctor beforehand.

Maitake Mushroom

Other Names: Grifola frondosa, hen of the woods, ram’s head mushroom

Maitake mushroom, also known as hen of the woods, is a type of medicinal mushroom that has been used for centuries in traditional Asian medicine to treat a variety of health conditions. It is believed to have anti-inflammatory and immune-boosting properties, and is often used to help relieve symptoms of conditions like heart disease, high blood pressure, and diabetes.

Maitake mushrooms are native to Asia and North America, and have been harvested for centuries by indigenous people for both food and medicine. Today, they are widely available in supplement form as powders or extracts, which can be taken by mouth or applied topically to help ease various symptoms related to different health conditions.

Some of the most common uses of maitake mushrooms include reducing inflammation in the body, boosting immunity, and improving heart health. They may also be used to help manage symptoms associated with certain types of cancer and other chronic conditions.

Stacks Well With: Methylene Blue

Memantine

Neuroprotective and anti-Alzheimer’s drug
Other Names: Namenda

Memantine is a drug that is used primarily to treat symptoms of Alzheimer’s disease and other neurodegenerative disorders. It was originally developed in the 1960s by a German pharmaceutical company, and was designed to target glutamate receptors in the brain.

Today, memantine is commonly prescribed as a supplement to help improve memory, cognition, and overall functioning in patients with neurodegenerative conditions. It is generally considered safe and well-tolerated, although some studies have shown that it may be associated with certain side effects such as anxiety, nausea, and dizziness.

Despite these potential risks, memantine remains an important treatment option for patients suffering from Alzheimer’s disease and other forms of dementia. It has been shown to help improve cognitive functioning, relieve behavioral disturbances associated with dementia, and enhance quality of life for patients and their caregivers alike.

Methylene Blue

Other Names:

Methylene Blue is a potent supplement that has been used for centuries to treat a variety of symptoms. Originally developed as an anti-malarial drug, it was later found to be effective in treating other conditions and disorders.

Methylene Blue is commonly used to treat symptoms of depression, anxiety, and even Alzheimer’s disease. It has also been shown to improve cognitive function in patients with dementia and other neurodegenerative diseases.

While there are some potential side effects associated with this powerful supplement, most people tolerate it well and experience significant improvements in their symptoms when taking Methylene Blue regularly.

Mucuna Pruriens

Natural dopamine
Other Names: Velvet Bean, Magic Velvet Bean, Cowhage, Atmagupta, Couhage, Cowitch, Cow-Itch Plant, Dolichos Pruriens, Feijao Macaco, HP 200, HP-200, Kapi Kacchu, Kapikachchhu, Kapikachhu, Kapikachu, Kaunch, Kawach, Kawanch, Kevanch, Kiwach, Mucuna, Mucuna hirsuta, Muc

Mucuna pruriens, also known as velvet bean, is a plant native to Africa and Asia that has been used for thousands of years as a medicinal supplement. It is typically taken to treat a variety of symptoms, including anxiety and depression, low energy levels, sexual dysfunction, and more.

The origins of Mucuna pruriens can be traced back across many different cultures and traditions. It has long been used in Ayurvedic medicine in India, where it was esteemed for its ability to increase energy levels and improve overall health. Today, it is commonly used all around the world as a natural remedy for a range of conditions.

There are several different ways that people can take Mucuna pruriens to help manage their symptoms. Some prefer to take it in tablet or capsule form, while others may prefer using a powder or liquid preparation instead. Additionally, some choose to take supplements containing Mucuna pruriens alongside other herbal formulations designed to boost mental health and well-being.

NAC

Versatile and effective all-round cognitive supplement
Other Names: N-acetylcysteine, Acetylcysteine, Acetadote, Fluimucil, Mucomyst

NAC, or n-acetyl cysteine, is a supplement that is used to treat a variety of different symptoms and conditions. It is believed to have its origins in the 1960s, when research first began to explore its possible benefits for preventing and treating respiratory tract infections like bronchitis and pneumonia.

Today, NAC is most commonly used as a treatment for chronic obstructive pulmonary disease (COPD), a debilitating lung condition that affects millions of people worldwide. It is also used to help reduce symptoms associated with asthma, as well as other respiratory conditions like cystic fibrosis and pulmonary fibrosis.

Additionally, NAC has been shown to have antioxidant properties, making it useful in the treatment of certain neurological disorders like Parkinson’s disease. It may also be effective in reducing the severity of some psychiatric disorders like addiction and depression.

NALT

Effective, natural way to support dopamine
Other Names: N-Acetyl-L-tyrosine, Tyrosine, NALT

NALT, or N-acetyl-L-tyrosine, is a dietary supplement that is commonly used to address a number of different symptoms and conditions. The origins of this supplement date back to the 1960s, when it was first developed as a pharmaceutical treatment for Parkinson’s disease. Since then, it has been used to help boost energy levels, improve mood and cognitive function, and ease stress and anxiety.

Today, NALT is commonly used by those who are looking to improve their overall physical and mental performance. It is typically taken in capsule or powder form along with other supplements like caffeine or L-theanine for enhanced results.

Some users also take NALT as part of a daily regimen for reducing inflammation and boosting overall health. Overall, NALT is considered to be a safe and effective supplement that can provide various benefits for those looking to enhance their physical and mental performance.

Nicotine

Not just for smokers anymore
Other Names: 3-(1-Methyl-2-pyrrolidinyl) pyridine

Nicotine is a natural compound that is found in the leaves of certain plants, including tobacco. It is typically used as a supplement to help people manage symptoms like anxiety and depression, as well as to promote focus and concentration.

Although nicotine can have some negative side effects when consumed in large doses, it has been used for centuries as a natural remedy for a variety of ailments.

The origins of nicotine can be traced back to ancient South American cultures, where it was used for its medicinal properties by indigenous tribes. Today, it continues to be widely used by people all over the world as a way to manage mental health issues and improve cognitive function.

Some may also use nicotine supplements to help them quit smoking or reduce their dependence on other substances like caffeine or alcohol.

Stacks Well With: Methylene Blue

Noopept

World’s #1 selling nootropic (and for good reason)
Other Names: n-phenylacetyl-l-prolylglycine ethyl ester

Noopept is a powerful nootropic supplement that was originally developed in Russia as a treatment for cognitive disorders like Alzheimer’s disease and dementia.

It works by improving the overall functioning of the brain by increasing levels of certain neurotransmitters like acetylcholine and glutamate, both of which are known to be important for higher cognition and memory.

In addition to its use as a treatment for memory loss, Noopept is also commonly used as a cognitive enhancer, helping people to boost their focus, concentration, and attention. It can also help improve mood and reduce feelings of stress and anxiety.

Overall, Noopept is an effective and powerful supplement that has been shown to have beneficial effects on many different aspects of brain health and function.

Oat Straw

Herbal nerve tonic
Other Names: Wild green oats

Oat straw supplements are a popular herbal remedy made from the dried stems and leaves of the oat plant. They have been used for centuries to treat a variety of ailments, including anxiety, insomnia, and fatigue.

There is some scientific evidence to support the use of oat straw supplements for cognitive enhancement. One study found that oat straw supplementation improved attention span and reaction time in healthy adults.

The mechanism of action for the cognitive benefits of oat straw supplements is not fully understood, but it is thought to be related to the high levels of flavonoids present in the oats.

Flavonoids are a type of phytonutrient that has been shown to have neuroprotective effects. If you are looking for a safe and effective way to improve your cognitive function, oat straw supplements may be worth considering.

Oxiracetam

Extremely popular synthetic learning and memory aid
Other Names:

Oxiracetam is a nootropic supplement that has been used for many years to help improve memory, learning, and focus. It was originally developed in the 1970s by a team of Hungarian scientists, and was initially used as a treatment for Alzheimer’s disease. However, it quickly became popular among the general public due to its ability to enhance cognitive function and increase productivity.

Today, oxiracetam is commonly used to treat symptoms like memory loss, poor concentration, and mental fatigue. It is also often taken by students and professionals who need to stay focused and alert during long periods of study or work. Additionally, some people use it as a cognitive enhancer in order to improve their overall brain health and performance.

Overall, oxiracetam is a powerful nootropic supplement that can offer many benefits for those looking to enhance their memory, learning ability, focus, and overall brain health.

Phenibut

Extremely powerful anti-anxiety drug developed by the Soviet space agency
Other Names: Fenibut, 4-Amino-3-phenylbutanoic acid, Phenylgamma

Phenibut is a powerful nootropic supplement that has origins in the Soviet Union. It is believed to help improve cognitive function and boost mental clarity, making it popular among students and professionals who need to stay focused and productive for long periods of time.
Phenibut is a powerful nootropic supplement that has origins in the Soviet Union.

It is believed to help improve cognitive function and boost mental clarity, making it popular among students and professionals who need to stay focused and productive for long periods of time. Additionally, Phenibut is often used to treat symptoms of anxiety, stress, and insomnia, as it can promote feelings of calmness and relaxation without causing drowsiness.

Additionally, Phenibut is often used to treat symptoms of anxiety, stress, and insomnia, as it can promote feelings of calmness and relaxation without causing drowsiness. While there is still some debate over the safety and effectiveness of Phenibut, many people have reported positive results when using this supplement.

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Phenylpiracetam

Closest legal alternative to Adderall
Other Names: Fonturacetam, Carphedon, 4-Phenyl-2-pyrrolidone-1-acetamide

Phenylpiracetam is a powerful nootropic supplement that was originally developed in Russia as a way to improve focus and concentration, reduce fatigue, and enhance physical stamina.

This popular supplement is typically used to treat symptoms such as ADHD, anxiety, memory loss, depression, and brain fog. It is believed to work by affecting various neurotransmitter systems in the brain, including dopamine and norepinephrine, which are involved in regulating mood, energy levels, cognitive function, and stress response.

There is some evidence from clinical studies that phenylpiracetam may help to improve overall cognitive function and learning ability in people with conditions like Alzheimer’s disease or other forms of dementia. Additionally, it has been shown to have positive effects on physical performance and athletic endurance.

Overall, phenylpiracetam is widely considered to be a safe and effective nootropic supplement that can help to boost mental clarity and promote physical vitality.

Phosphatidylcholine

Crucial component of all neural cells
Other Names: PC

Phosphatidylcholine, also known as PC, is a type of phospholipid that is found in the cells of many different types of organisms. This supplement is believed to offer several health benefits, including improved cognitive function, reduced cholesterol levels, and reduced symptoms of anxiety and depression.

The origins of phosphatidylcholine can be traced back to early cell biology research in the mid-20th century. Scientists discovered that this compound was an essential building block of cellular membranes, and its importance for various biological functions was soon understood.

Today, phosphatidylcholine is commonly used as a treatment for various mental and physical ailments. It is thought to promote brain health by improving communication between brain cells and helping to protect against age-related cognitive decline. Additionally, it may help lower cholesterol levels by preventing absorption of dietary fats in the gut.

Phosphatidylcholine may also be helpful for reducing symptoms associated with anxiety and depression, including insomnia, stress, irritability, restlessness, and low moods.

Phosphatidylserine

Critical building block of your braincells
Other Names: PS, PS Sharp, PS-100

Phosphatidylserine, or PS, is a dietary supplement that is believed to have a wide range of health benefits. This supplement is derived from soy lecithin and has been used by people for everything from mood enhancement and sports performance to improved cognitive function and prevention of age-related memory loss.

While the origins of PS as a dietary supplement are not entirely clear, it appears to have been discovered around 1900 by Russian scientists who were studying its effects on the nervous system. Today, PS is most commonly used for managing symptoms associated with anxiety and depression, improving cognitive abilities in elderly people, and enhancing athletic performance.

There is some scientific evidence showing that PS supplementation can be effective in reducing symptoms related to depression and anxiety, particularly in individuals experiencing mild-to-moderate symptoms. Additionally, there is some evidence suggesting that PS may help improve cognitive function by promoting healthy brain cell growth and protecting against age-related memory loss.

Whether you are looking for an edge in your athletic performance or simply want to maintain healthy brain function as you age, PS could be a great option for you.

Picamilon

A safer potential alternative to Xanax
Other Names: pycamilon, pikamilon, nicotinoyl-GABA, pikatropin

Picamilon is a dietary supplement that is commonly used to treat a variety of symptoms and conditions, including anxiety, stress, depression, and insomnia. It was originally developed in the Soviet Union in 1969, and its use has since spread throughout Europe and the United States.

Picamilon works by binding GABA, a neurotransmitter that plays a role in regulating mood and sleep patterns, with niacin, an essential vitamin that helps support brain health. This combination causes an increase in GABA levels within the brain, which can help promote feelings of calmness and reduce symptoms of stress or anxiety.

Many people also take picamilon to help improve cognitive function and boost overall mental performance. Studies have shown that it can help increase focus and concentration while reducing mental fatigue. Additionally, picamilon has been shown to increase blood flow to the brain, which may contribute to improved memory and learning ability.

Overall, picamilon is a powerful supplement that can be used to treat a wide range of mental health issues. If you are experiencing symptoms like anxiety or depression, or if you want to improve your cognitive abilities, this supplement may be right for you.

Pine Bark Extract

All natural ADHD remedy
Other Names: Proanthocyanidins, Pine Bark Maritime Extract, Pycnogenol®

Pine bark extract is a powerful nutritional supplement that has been used for centuries in traditional Chinese medicine. This extract is derived from the pine needles and bark of certain pine trees and is known for its high antioxidant content.

In addition to its antioxidant properties, pine bark extract has also been shown to have anti-inflammatory effects, which may help to treat a variety of conditions and symptoms, including joint pain, skin inflammation, and allergies. Some studies have even found that this supplement can reduce the risk of cardiovascular disease and help to improve cognitive function.

Overall, pine bark extract is a versatile and effective supplement that can be used to treat a range of different conditions and symptoms. Whether you are looking for relief from joint pain or improved mental clarity, this supplement could be right for you!

Piracetam

The original nootropic
Other Names: Nootropil, Lucetam, Biotropil, Stimulan, Breinox

Piracetam is a popular nootropic supplement that has been used for many years to help improve cognitive function, memory, and focus. It is believed to have originated in the 1960s, when researchers first discovered its ability to enhance brain activity.

Today, it is typically used to manage symptoms of conditions like Alzheimer’s disease, dementia, and stroke recovery by improving brain plasticity and neural communication. Some people also use Piracetam to help improve their concentration levels and reduce feelings of stress or anxiety.

While the research on this supplement is still ongoing, it seems to be an effective treatment option for individuals looking to boost their mental performance or support healthy brain aging.

Pramiracetam

A more potent version of the original piracetam
Other Names: Pramistar

Pramiracetam is a nootropic supplement that has been used for many years to treat a variety of cognitive and neurological symptoms. Its origins can be traced back to the 1970s, when it was developed by the pharmaceutical company Parke-Davis as an experimental drug.

Today, pramiracetam is widely used to improve memory, focus, and learning ability in people suffering from conditions such as Alzheimer’s disease and other forms of dementia. It is also commonly prescribed off-label to help enhance brain function and prevent cognitive decline in healthy individuals.

In addition to its effects on cognition, pramiracetam has also been shown to provide significant relief from symptoms related to sleep disturbances, depression, and anxiety. Because of these properties, it is often used by those struggling with stress or low moods.

Overall, pramiracetam is considered a powerful tool for boosting brain health and functioning at any age. Whether you are looking for relief from cognitive decline or simply want to maximize your mental performance, this supplement could be an excellent choice for you.

PRL-8-53

Memory enancer
Other Names: Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate

PRL-8-53 is a dietary supplement that was originally developed in the 1970s by researchers at the University of Rhodesia, now known as Zimbabwe. It has been used for a variety of purposes, including enhancing memory and cognitive function, reducing stress and anxiety, and improving sleep quality.

The exact mechanisms by which this supplement works are not well understood, though some research suggests that it may affect levels of certain neurotransmitters in the brain. It is also believed to interact with receptors for the hormone melatonin, which plays an important role in regulating sleep cycles.

Overall, PRL-8-53 appears to be a safe and effective option for those looking to boost their cognitive performance or improve the quality of their sleep.

Pyrroloquinoline Quinone PQQ

Powerful Mitochondria Booster
Other Names: pyrroloquinoline quinone, PQQ, methoxatin, Coenzyme pqq

Pyrroloquinoline quinone, or PQQ, is a naturally occurring compound that is found in a number of foods and supplements.

It has been shown to have a wide range of health benefits, including promoting energy metabolism, supporting cognitive function, and reducing inflammation. PQQ is commonly used to treat symptoms of various conditions, such as chronic fatigue syndrome, depression, and ADHD.

It may also be helpful for improving sleep quality and maintaining healthy skin. Overall, PQQ is a powerful natural supplement that can benefit a variety of different aspects of health and wellbeing.

Reishi Mushroom

A staple in Eastern medicine
Other Names: Lingzhi, Ganoderma lucidum, Jong Siryongji, Mannentake

Reishi mushroom, also known as lingzhi mushroom, is a medicinal fungus traditionally used in Chinese medicine to treat a variety of ailments. This powerful natural remedy is believed to have anti-inflammatory, antiviral, and immune-boosting properties, making it highly effective for treating everything from respiratory infections and chronic fatigue to high blood pressure and anxiety.

Reishi mushrooms are thought to have originated in China and Japan, but they have been used for centuries in many different parts of Asia. Today, this remarkable supplement is widely available both online and at health food stores, where it can be found in capsule or liquid extract form.

There are many different symptoms that reishi mushrooms may be used to treat, including colds and flu, hypertension, liver disease, asthma, allergies, insomnia, chronic pain, depression and anxiety. Due to its various therapeutic properties and wide range of uses, reishi mushrooms are considered one of the most versatile natural supplements available today.

Rhodiola Rosea

Ancient herbal performance enhancer
Other Names: Golden root, arctic root, king’s crown

Rhodiola rosea, also known as golden root or rose root, is a popular herbal supplement that has been used for centuries in traditional medicine. Originating in Siberia and northern Asia, this plant extract has long been prized for its many therapeutic properties, including its ability to reduce symptoms of stress and anxiety, boost energy levels and athletic performance, and promote general wellbeing.

Today, rhodiola rosea is commonly used to treat a wide range of conditions and ailments, from mild depression to chronic fatigue syndrome. In addition to its therapeutic effects, this herbal supplement is considered safe and well-tolerated by most users.

Saffron

Other Names: Crocus sativus

Saffron is a popular herbal supplement that has been used for centuries as a remedy for various health conditions. Originally native to the Mediterranean region, saffron is now also cultivated in other parts of the world, including Asia and North America.

The main use of saffron is to treat symptoms of depression, anxiety, and other mental health disorders. It has also been shown to help relieve the symptoms of PMS, including mood swings and irritability. Additionally, saffron may have beneficial effects on heart health, improving circulation and reducing blood pressure levels.

Sarcosine

Prescription drug for Alzheimer’s and neuroprotection
Other Names: N-methylglycine

Sarcosine, also known as N-methylglycine, is a naturally occurring amino acid that is produced by the human body. It has been used in supplement form to help treat a number of different symptoms, including depression, schizophrenia, and drug addiction. Some research has also suggested that it may be useful in promoting weight loss and improving cognition.

Although the origins of sarcosine are somewhat unclear, it is believed to have first been discovered by German chemist Justus von Liebig in 1847. Since then, its use as a supplement has become increasingly common, particularly among people dealing with mental health issues or drug addictions.

One of the main uses for sarcosine supplements is in treating symptoms related to schizophrenia. This condition is characterized by distorted thoughts and perceptions, hallucinations, and other neurological issues. Sarcosine has been shown to help improve these symptoms by reducing levels of an amino acid called glutamate in the brain.

Additionally, sarcosine may be helpful for individuals suffering from depression and addiction issues. Research suggests that this supplement can help increase levels of dopamine and serotonin in the brain – two important neurotransmitters associated with mood regulation and happiness. As such, sarcosine may be able to help alleviate some of the symptoms associated with depression and addiction disorders.

Selegiline

A neuroprotectant also prescribed under the name Deprenyl
Other Names: Deprenyl, Emsam

Selegiline is a type of supplement that is used to treat a variety of symptoms, including depression, anxiety, and cognitive impairment. It is derived from an amino acid called L-tyrosine, and was originally discovered by Russian scientists in the 1960s.

Today, selegiline is commonly prescribed by doctors to treat conditions like Parkinson’s disease and ADHD. It works by increasing the levels of certain neurotransmitters in the brain, which helps to regulate mood and cognition. Additionally, selegiline may also have some anti-aging properties due to its ability to stimulate certain growth factors involved in cellular repair.

Overall, selegiline is a powerful supplement that can be used to manage a wide range of conditions related to mood and cognition. However, it should always be taken under the supervision of a healthcare professional, as there may be some potential side effects associated with this drug.

Sulbutiamine

Highly stimulating vitamin B derivative
Other Names: Arcalion

Sulbutiamine is a synthetic compound that was originally developed in Japan as a treatment for Alzheimer’s disease. It is believed to work by increasing levels of certain neurotransmitters in the brain, which helps improve cognitive function and reduce symptoms like memory loss and confusion.

Today, sulbutiamine is commonly used as a supplement to help improve focus, energy levels, and overall mental performance. Some users also take it to help manage symptoms of depression or anxiety.

Taurine

Not just for energy drinks
Other Names: Aminoethylsulfonic acid, Taurineold

Taurine is a popular supplement that has origins in both traditional Chinese medicine and modern scientific research. While it is primarily known for its ability to reduce symptoms of anxiety and insomnia, it is also used to support the health of the cardiovascular system, boost energy levels, and improve overall cognitive function. Additionally, many people take taurine supplements for their antioxidant properties, as well as for their potential benefits for muscle growth and recovery.

The exact mechanisms by which taurine works are not fully understood by scientists, but it is believed to influence various chemical signaling pathways in the brain. Taurine supplements can be found online or at most health and nutrition stores, and they are generally considered safe when used appropriately. However, they may interact with certain medications or medical conditions, so it is always advisable to speak with your doctor before beginning any new supplement regimen.

Theacrine

Coffee alternative extracted from the tea plant
Other Names: TeaCrineTM, 1,3,7,9-tetramethyluric acid

Theacrine is a natural supplement that is believed to help improve mood, focus, and energy levels. It is believed to have its origins in China, where it was traditionally used in tea as an energizing beverage.

Today, theacrine is used primarily as a nootropic supplement, and is often taken to help alleviate symptoms of fatigue or low mood. Some people also use it to help enhance mental clarity or focus, making it a popular supplement among students and other busy professionals. Additionally, some users claim that theacrine can help improve athletic performance by reducing feelings of pain or discomfort during physical activity.

Overall, theacrine is considered a safe and effective supplement with a wide range of possible benefits for those looking to boost their physical and mental well-being.

Uridine Monophosphate

One of the basic building blocks of your body
Other Names: UMP, Uridine Monophosphate

Uridine Monophosphate, or UMP, is a popular dietary supplement that has gained popularity in recent years for its purported benefits to brain health. While the origins of UMP are not entirely clear, it is believed to have originated from the natural chemical uridine, which is found in many foods and can also be produced synthetically.

UMP is used for a variety of different symptoms, including improving mental performance and memory, increasing focus and concentration, and protecting against cognitive decline associated with aging.

It has also been shown to help improve symptoms related to mood disorders like depression and anxiety. Overall, UMP is considered a safe and effective supplement that may help promote overall brain health and wellness.