ACP-105 – Health benefits, side effects, how to use, and more!

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Key Information

ACP-105 enhances focus, motivation, and memory

ACP-105 works by increasing key neurotransmitters and protecting brain cells from damage

ACP-105 is safer than Adderall and other smart drugs

ACP-105 is made of natural ingredients and has no major side effects or addiction risk.

ACP-105 supports learning, intelligence, and cognition

ACP-105 improves blood flow, oxygen, and nutrients to the brain, which fuels neuroplasticity and IQ

ACP-105 is legal and available without a prescription

ACP-105 is an over-the-counter supplement that can be bought online from verified sources.

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In the world of nootropics and performance enhancement, ACP-105 has emerged as a potent compound with promising potential. As a selective androgen receptor modulator (SARM), ACP-105 has garnered attention for its cognitive-enhancing properties and muscle-building effects. At Holistic Nootropics, our mission is to provide evidence-based, holistic strategies for optimizing mental health and cognitive performance. In this comprehensive guide, we’ll dive deep into ACP-105, exploring its mechanism of action, benefits, safety considerations, and practical applications. Learn More: What are Nootropics? The Ultimate Beginners Guide To Cognitive Enhancers

How ACP-105 Works

ACP-105 functions as a partial agonist of androgen receptors, selectively binding to these receptors in skeletal muscle and brain tissue.[1][2] This selective binding allows ACP-105 to exert its effects on specific target tissues while minimizing unwanted side effects associated with non-selective androgen receptor activation.

In the brain, ACP-105 has been shown to increase androgen receptors in the hippocampus, a region crucial for memory formation and cognitive function.[3] By modulating androgen signaling in this area, ACP-105 may enhance cognitive performance, particularly in domains such as memory, concentration, and alertness.

When it comes to muscle growth, ACP-105 works by reducing high-density lipoproteins and increasing lean muscle mass without causing muscle wasting.[1][3] This selective anabolic effect allows for targeted muscle growth and strength gains while minimizing the risk of adverse effects on other tissues.

Benefits of ACP-105

The unique mechanism of action of ACP-105 translates into a range of potential benefits for both cognitive enhancement and physical performance. Let’s explore some of the key advantages of this promising SARM:

  • Cognitive Enhancement: By increasing androgen receptors in the hippocampus, ACP-105 may improve memory, concentration, and alertness.[3] This cognitive boost can be particularly beneficial for individuals seeking to optimize their mental performance, whether for academic pursuits, professional demands, or personal growth. Learn More: Get in the Zone: Best Nootropics for ADHD & Focus
  • Muscle Growth and Fat Loss: ACP-105 has been shown to increase strength and endurance while reducing abdominal and visceral fat.[4] For athletes, bodybuilders, and fitness enthusiasts, these effects can support the pursuit of a lean, muscular physique and enhance overall physical performance.
  • Potential Therapeutic Uses: Beyond its nootropic and performance-enhancing properties, ACP-105 may have therapeutic potential in various contexts. It has been investigated for the treatment of age-related cognitive decline, muscle wasting conditions like sarcopenia and cachexia, and bone degenerative disorders such as osteoporosis.[1][2][3]
  • Low Risk of Side Effects: Compared to anabolic steroids, ACP-105 offers a more favorable safety profile. It is non-aromatizing, meaning it does not convert to estrogen and avoids estrogenic side effects.[2] Additionally, ACP-105 has not been shown to cause liver or prostate damage, making it a potentially safer alternative for those seeking performance enhancement.[1]

Dosage and Cycling

When it comes to using ACP-105, proper dosage and cycling protocols are essential for maximizing benefits while minimizing risks. The recommended dosage of ACP-105 is 1mg/kg body weight per day.[2] For men, this typically translates to 10-20mg per day, while women may opt for a lower dosage of 5-10mg per day.

Cycle length is another important consideration. A typical ACP-105 cycle lasts 8-14 weeks, allowing sufficient time for the compound to exert its effects while avoiding potential long-term risks. It’s crucial to incorporate post-cycle therapy (PCT) after an ACP-105 cycle to prevent testosterone suppression and maintain hormonal balance.[1][4]

ACP-105 Stacks

While ACP-105 can be used on its own, some individuals may choose to stack it with other compounds to target specific goals. Here are a few popular ACP-105 stacks:

  • Cutting Stack: Combining ACP-105 with Cardarine and Stenabolic can create a powerful cutting stack aimed at maximizing fat loss while preserving lean muscle mass.
  • Bulking Stack: Pairing ACP-105 with LGD-4033 and MK-677 can support rapid muscle growth and strength gains during a bulking phase.
  • Cognitive Enhancement Stack: Stacking ACP-105 with Noopept and Citicoline may synergistically enhance cognitive function, promoting better memory, focus, and mental clarity. Learn More: Best Nootropics For Studying, Memory, and Focus

Safety and Side Effects

While ACP-105 is generally well-tolerated, it’s important to be aware of potential side effects, particularly at higher doses. Some individuals may experience headaches, fatigue, or exhaustion due to testosterone suppression.[4] It’s worth noting that ACP-105 is a research chemical and has not been approved by the FDA for human use. Pregnant and nursing women, as well as children, should avoid using ACP-105.

ACP-105 vs Other SARMs

To better understand the unique properties of ACP-105, let’s compare it to a few other popular SARMs:

SARMAnabolic:Androgenic RatioHalf-LifeTypical Dosage
ACP-105High anabolic selectivity[1]5 hours[1]10-20mg/day
Ostarine (MK-2866)3:1[5]24 hours[5]10-25mg/day
Testolone (RAD140)90:1[6]16-20 hours[6]10-20mg/day

Where to Buy ACP-105

When purchasing ACP-105 or any research chemical, it’s crucial to choose reputable vendors that prioritize quality, purity, and third-party testing. Avoid suppliers that make unrealistic claims or lack transparency about their products. Stick with trusted vendors known for their commitment to providing high-quality, lab-tested SARMs. Learn More: Amazon’s Fake/Counterfeit Supplement Problem

ACP-105 Discussions on Reddit

Reddit has become a valuable platform for individuals to share their experiences, insights, and questions about various nootropics and performance-enhancing compounds. Let’s explore some notable discussions about ACP-105 on Reddit:

ACP-105 Experiences and Results

Zero sides, strength gains were better than I expected considering I was in a significant caloric deficit. No water retention at all. Its probably the best Cutter Ive used if side effects are your main concern.

u/Admirable_Spare797 in discussion ‘Worth running ACP105?’

Comparing ACP-105 to Other SARMs

In my experience, ACP was more suppressive than Osta , but on the other hand, ACP had little impact on lipids and liver enzymes. Osta was much harsher on lipids and liver for me, go figure.

u/Admirable_Spare797 in discussion ‘Worth running ACP105?’

ACP-105 Dosage and Cycle Recommendations

I took two doses of 7.5mg, one at 8:00 in the morning and the other at 16:00 in the afternoon. IMO is a quite good SARM, It will dry you out very well, if you are bulking It can give you about 5-7lb of quality muscle.

u/SmartBus5015 in discussion ‘Acp-105 dosage’

These discussions highlight the importance of personal experimentation, careful dosing, and monitoring individual responses when using ACP-105 or any other research chemical. It’s essential to approach these compounds with caution, conduct thorough research, and prioritize safety above all else.

Frequently Asked Questions

1. Is ACP-105 suppressive?
While ACP-105 is considered less suppressive than some other SARMs, it can still cause testosterone suppression, particularly at higher doses or with prolonged use. Post-cycle therapy (PCT) is recommended to help restore hormonal balance after an ACP-105 cycle.

2. How long does ACP-105 take to work?
The effects of ACP-105 may be noticeable within the first few weeks of use, but it typically takes several weeks to experience the full benefits. Consistent use and proper dosing over the course of a cycle are necessary to maximize results.

3. Can women take ACP-105?
Yes, women can take ACP-105, but at lower doses compared to men. A typical dosage for women is 5-10mg per day, and cycle lengths should be shorter, around 6-8 weeks. As with any performance-enhancing compound, women should be cautious and monitor their individual responses closely.

4. What PCT is needed after an ACP-105 cycle?
Post-cycle therapy (PCT) is crucial after an ACP-105 cycle to help restore natural testosterone production and maintain gains. Common PCT protocols include compounds like Clomid or Nolvadex, used for several weeks following the end of the cycle. Consult with a healthcare professional or experienced coach to determine the most appropriate PCT protocol for your individual needs.

5. Is ACP-105 legal?
The legal status of ACP-105 varies by jurisdiction. In many countries, including the United States, ACP-105 is considered a research chemical and is not approved for human consumption. It is important to check your local laws and regulations before purchasing or using ACP-105 or any other research chemical.


ACP-105 is a promising SARM with potential benefits for cognitive enhancement, muscle growth, and fat loss. Its selective binding to androgen receptors in the brain and skeletal muscle allows for targeted effects while minimizing the risk of adverse reactions. However, as with any research chemical, caution and responsible use are paramount.

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Erik Abramowitz is a certified Nutritional Therapy Practitioner (NTP), Naturopathic Doctoral student, health coach, and father. He is the primary content creator for and the host of the Holistic Nootropics Podcast.

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