Best Nootropics For Studying, Memory, and Focus

Oxiracetam is a synthetic racetam-type nootropic, meaning it modulates the AMPA and NDMA receptors in your brain.

It increases the amount of the neurotransmitter acetylcholine, which can ultimately help you study better.¹Gouliaev AH, Senning A. Piracetam and other structurally related nootropics, Brain Res Brain Res Rev. 1994

Oxiracetam has clinically proven benefits for cognition, and many users note that it can increase their attention span, information retention, and overall cognitive processes.

In short, it can help you get “in the zone” while studying.²Fordyce DE, et al. Enhancement of hippocampally-mediated learning and protein kinase C activity by oxiracetam in learning-impaired DBA/2 mice, Brain Res. 1995

This nootropic also has a mild stimulatory effect that can keep you alert and on task. However, it is not nearly as powerful as a drug like Adderall, so you don’t need to worry about crashing later.

Oxiracetam achieves its effects through much more subtle and sustainable means so that you can take it frequently without fear.

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Magnesium is an essential mineral for various cognitive functions, including studying. We know that studying is an extensive process requiring deep concentration, learning and memorization.³Kateba Al-Ghazali, Sana Eltayeb, Ayesha Musleh, Tamara Al-Abdi, Vijay Ganji, and Zumin Shi, Serum Magnesium and Cognitive Function Among Qatari Adults, Front Aging Neurosci. 2020

Research suggests that increasing the intake of dietary magnesium can help in enhancing our cognitive abilities such as learning, focusing and memorization. This postulation is supported by extensive clinical evidence suggesting that insufficient levels of magnesium in the body are associated with cognitive impairment.⁴Inna Slutsky , Nashat Abumaria, Long-Jun Wu, Chao Huang, Ling Zhang, Bo Li, Xiang Zhao, Arvind Govindarajan, Ming-Gao Zhao, Min Zhuo, Susumu Tonegawa, Guosong Liu, Enhancement of learning and memory by elevating brain magnesium, Neuron. 2010⁵Jürgen Vormann, Magnesium: nutrition and metabolism, Mol Aspects Med. 2003

It is well known that different forms of magnesium can have different bioavailabilities; hence, a complex formulation consisting of various forms of elemental magnesium such as those found in Magnesium Breakthrough can significantly increase the likelihood of receiving all the cognitive benefits of magnesium.⁶Abdullah M. Al Alawi,corresponding author,Sandawana William Majoni, and Henrik Falhammar , Magnesium and Human Health: Perspectives and Research Directions, Int J Endocrinol. 2018⁷Jan Philipp Schuchardt and Andreas Hahn, Intestinal Absorption and Factors Influencing Bioavailability of Magnesium-An Update, Curr Nutr Food Sci. 2017

Aniracetam is a cousin of oxiracetam and is also a racetam. It works through a similar mechanism, but it does have a few distinctions.

Like oxiracetam, many people say that aniracetam is great for stimulated-but-controlled focus and memory. And, there are plenty of clinical studies to back this up.⁸Shirane M, Nakamura K. Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP, Brain Res. 2001 ⁹Ingvar M, et al. Enhancement by an ampakine of memory encoding in humans, Exp Neurol. 1997

It is also famous for elevating mood. Feeling an emotional boost could put you in a better headspace to crack open the books and get to work. Keep in mind this is not the manic high of a drug like Adderall, but a more gentle effect.

Aniracetam and oxiracetam are both great choices, but aniracetam might be better if you are looking for a mood boost as well.¹⁰Nakamura K, Tanaka Y.. Antidepressant-like effects of aniracetam in aged rats and its mode of action, Psychopharmacology (Berl). 2001

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Noopept is very similar to the racetams listed above, in that it’s a synthetic nootropic that can improve studying through the acetylcholine system.

It also stimulates what’s called brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF).

BDNF and NGF are the processes that grow and repair new neurons.

Building and repairing neurons is critical for maintaining the health of the brain and forming new memories.

By increasing these abilities, noopept can help you retain whatever you’re learning so you can recall it easier come exam time.

Noopept is also famous for its stimulating effects. It is one of the most potent nootropics out there, increasing the energy even in minimal doses.

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Citicoline is the perfect addition to your studying stack if you are going to use oxiracetam, aniracetam, or noopept.

Those nootropics can use up the choline stores in your brain, meaning it’s a good idea to supplement with an additional source.

The racetams can then turn it into acetylcholine, improving your focus and memory in the process.

Also, if your brain starts running low on choline, you run the risk of a headache. This pain is obviously something you DON’T want while studying for an important test.

We recommend always combining racetams with something like citicoline for this reason.

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Bacopa is an all-natural nootropic in use for millennia in Eastern cultures. It may be one of the original study drugs.

There is archeological evidence that monks and scholars used bacopa monnieri to help them memorize prayers and manuscripts thousands of years ago!

Nothing has changed all that much, and Bacopa is still a fantastic herb for hitting the books if you’re a modern student. Modern research also suggests that this nootropic is useful for studying.

Bacopa monnieri contains organic compounds called “bacosides” that may speed up mental processing and increase information retention according to research.

As another bonus for students, bacopa is an adaptogen, meaning it can help the body deal with stress and help the anxiety of studying for exams.

Bacopa can keep your hormones in balance so that you can focus effectively on the work in front of you.

We consider bacopa a must-have for any student looking for a calm and collected focus.

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Adrafinil is an excellent alternative to Adderall if you are looking to stay up all night cramming.

This nootropic is actually a prodrug of the prescription drug Modafinil meaning that your body turns adrafinil into modafinil, but you do not need a prescription to buy it.

Adrafinil was initially created as an anti-narcoleptic drug to keep people up and alert for long periods.

This nootropic is used by militaries around the world to stay focused during taxing operations, and these effects can translate to studying for exams.

Adrafinil works by mildly stimulating your dopamine receptors (among others), although not nearly to the degree of Adderall.

This stimulation can give you an increase in focus and motivation while you study for long periods.

Adrafinil is legendary for its anti-fatigue effects, and it can help you power through a last-minute crunch.¹¹Battleday RM, Brem AK. Modafinil for cognitive neuroenhancement in healthy non-sleep-deprived subjects: A systematic review, Eur Neuropsychopharmacol. 2015 ¹²Milgram NW, et al. Oral administration of adrafinil improves discrimination learning in aged beagle dogs, Pharmacol Biochem Behav. 2000 ¹³Müller U, et al. Effects of modafinil on non-verbal cognition, task enjoyment, and creative thinking in healthy volunteers, Neuropharmacology. 2013

It is also pretty sustainable, without any serious crash to worry. Be mindful that it can cause insomnia in too high doses or taken too late at night.

Adrafinil has a relatively low side-effect profile for the most part.

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