Aniracetam: Benefits, Dosing, Where To Buy, And More!

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Key Information

Aniracetam is a potent nootropic

Aniracetam is a synthetic compound that can enhance memory, cognition, mood, and neuroprotection.

Aniracetam works on glutamate and acetylcholine

Aniracetam modulates the activity of glutamate receptors and increases the release of acetylcholine in the brain.

Aniracetam has few side effects

Aniracetam is generally well-tolerated, but may cause headaches, anxiety, or gastrointestinal upset in some users.

Aniracetam requires a choline source

Aniracetam depletes choline in the brain, so it is advisable to take a choline supplement, such as alpha-GPC or citicoline.

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In the ever-evolving world of nootropics, Aniracetam stands out as a potent cognitive enhancer with anxiolytic properties.

At Holistic Nootropics, we believe in demystifying the complex landscape of brain-boosting supplements, providing evidence-based insights to help you optimize your mental performance and well-being. In this comprehensive guide, we’ll dive deep into the science behind Aniracetam, its benefits, dosage, and safety considerations, empowering you to make informed decisions about incorporating this nootropic into your holistic mind-body health regimen.

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What is Aniracetam?

Aniracetam is a synthetic nootropic compound belonging to the racetam family, known for its cognitive-enhancing effects. Developed in the 1970s by Swiss pharmaceutical company Hoffmann-La Roche, Aniracetam has gained popularity for its ability to improve memory, focus, and mood, while reducing anxiety and stress.

Popular nootropoic for boosting focus and mood

Aniracetam by

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  • Good for memory and learning enhancement

  • Clinical studies show enhanced neuroprotection from age-related cognitive decline

  • Improves brain connectivity and helps with focus

  • Highly sustainable- no need for tolerance build up

  • Minimal side effects, can be taken every day

How Aniracetam Works

Aniracetam exerts its nootropic effects through several mechanisms:

  • Modulation of AMPA receptors: Aniracetam enhances the function of AMPA receptors, which are involved in glutamate neurotransmission, leading to improved synaptic plasticity and cognitive performance.1
  • Increased acetylcholine release: Aniracetam stimulates the release of acetylcholine, a neurotransmitter crucial for learning, memory, and attention.3
  • Neuroprotection: Aniracetam has been shown to protect neurons from oxidative stress and toxicity, promoting brain health and resilience.2

Compared to other racetams like Piracetam and Oxiracetam, Aniracetam is considered more potent and fast-acting, thanks to its higher bioavailability and lipid solubility.

Benefits of Aniracetam

Aniracetam offers a wide range of cognitive and mood-related benefits:

  • Enhanced memory and learning: Aniracetam has been shown to improve both short-term and long-term memory, as well as learning ability, in animal studies and human trials.4
  • Increased focus and attention: By modulating glutamate and acetylcholine neurotransmission, Aniracetam can enhance focus, concentration, and mental clarity.
  • Reduced anxiety and depression: Aniracetam has demonstrated anxiolytic and antidepressant-like effects in various animal models, suggesting its potential for managing mood disorders.5
  • Neuroprotection and cognitive decline prevention: Aniracetam’s neuroprotective properties may help prevent age-related cognitive decline and support brain health in the long term.6

Dosage and Administration

The recommended dosage for Aniracetam varies between 750-1500 mg per day, divided into two or three doses. It’s essential to start with a lower dose and gradually increase it to assess your individual tolerance and response. Aniracetam is fat-soluble, so it’s best to take it with meals containing healthy fats to enhance absorption.

To maximize the benefits and minimize the risk of tolerance, it’s advisable to cycle Aniracetam, taking breaks every few weeks or months. Stacking Aniracetam with choline sources like Alpha-GPC or Citicoline can help prevent headaches and optimize cognitive enhancement.

Aniracetam Safety and Side Effects

Aniracetam is generally well-tolerated, with few reported side effects. However, some users may experience:

  • Headaches
  • Anxiety
  • Insomnia
  • Gastrointestinal discomfort

To minimize side effects, start with a low dose, take Aniracetam with food, and maintain adequate choline intake. If you experience persistent or severe side effects, discontinue use and consult a healthcare professional.

Aniracetam vs Other Nootropics

NootropicCognitive BenefitsAnxiolytic EffectsNeuroprotection

Compared to other popular nootropics, Aniracetam stands out for its potent cognitive-enhancing and anxiolytic effects. Its unique combination of benefits makes it a versatile choice for those seeking to boost mental performance while managing stress and anxiety.

Frequently Asked Questions (FAQ) About Aniracetam

Is Aniracetam legal?

Aniracetam is legal to purchase and possess in most countries, including the United States, where it is sold as a dietary supplement. However, it’s essential to check your local laws and regulations before purchasing or consuming Aniracetam.

How long does it take for Aniracetam to work?

Aniracetam is known for its fast-acting effects, with many users reporting noticeable cognitive enhancement and mood improvement within 30-60 minutes of consumption. However, individual responses may vary.

Can Aniracetam be taken long-term?

While Aniracetam is considered safe for long-term use, it’s recommended to cycle the supplement to maintain its efficacy and minimize the risk of tolerance. Taking breaks every few weeks or months can help ensure sustained benefits.

What’s the best time of day to take Aniracetam?

The optimal time to take Aniracetam depends on your individual goals and tolerance. Many users prefer taking it in the morning or early afternoon to promote focus and productivity throughout the day. However, some may find that taking Aniracetam later in the day helps manage anxiety and stress without interfering with sleep.

Can Aniracetam help with social anxiety?

Yes, Aniracetam’s anxiolytic properties make it a popular choice for managing social anxiety. Many users report increased confidence, improved verbal fluency, and reduced anxiety in social situations when taking Aniracetam.

Where to Buy Aniracetam

When purchasing Aniracetam, it’s crucial to choose a reputable vendor that ensures product quality, purity, and safety. Look for suppliers that provide third-party lab testing results and have a proven track record of customer satisfaction.

At Holistic Nootropics, we’ve carefully vetted and compiled a list of trusted Aniracetam sources to help you make an informed decision.

Aniracetam by

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Aniracetam Powder by Research Chemical Depot

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Aniracetam by Nootropics Unlimited

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Aniracetam Discussions on Reddit

Aniracetam for Social Anxiety and Confidence

Aniracetam essentially created my career in public speaking and presenting. Found it 15 years ago and nothing has come close for verbal fluency and recall. It makes me feel unstoppable when presenting in front of people.

u/dras333 in discussion ‘What have been your experiences with aniracetam, coluracetam or pramiracetam?’

Many Reddit users report significant improvements in social situations, verbal fluency, and confidence when using Aniracetam. The anxiolytic effects of Aniracetam appear to be a key factor in these benefits, making it a popular choice for those seeking to manage social anxiety and enhance their public speaking abilities.

Aniracetam Dosage and Effects

750mg as needed. It works acutely for social interaction and speech fluidity. Longer term consistent use is more for cognitive decline benefits.

u/dras333 in discussion ‘I honestly believe Aniracetam is working’

Reddit discussions often revolve around finding the optimal Aniracetam dosage for individual needs. Many users find 750 mg to be an effective dose for acute cognitive and anxiolytic benefits, while long-term consistent use may provide neuroprotective effects against age-related cognitive decline.

Aniracetam Stacks and Comparisons

Pramiracetam and piracetam. I’ve heard very good things about pramiracetam too, which id like to try soon.

u/insaiyan17 in discussion ‘Am I the only that doesn’t feel the “acute” speech and anti-anxiety effects from Aniracetam?’

Aniracetam is often compared to other racetams, such as Piracetam and Pramiracetam, with many users finding Aniracetam to be more potent and effective for acute cognitive enhancement and anxiolytic effects. Stacking Aniracetam with other nootropics, like choline sources, can further optimize its benefits.


Aniracetam is a powerful nootropic that offers a unique combination of cognitive enhancement, mood improvement, and anxiolytic effects. Its fast-acting nature and potent benefits make it a popular choice among nootropic enthusiasts and those seeking to optimize their mental performance and well-being.

As with any nootropic, it’s essential to approach Aniracetam use with caution and respect, starting with low doses and gradually adjusting based on your individual response. By incorporating Aniracetam into a holistic approach to brain health, along with a balanced diet, regular exercise, and healthy lifestyle practices, you can unlock your cognitive potential and thrive in both personal and professional spheres.

Remember, the key to success with Aniracetam, or any nootropic, is to prioritize safety, listen to your body, and maintain a balanced, sustainable approach to cognitive enhancement. At Holistic Nootropics, we believe in empowering our readers with the knowledge and tools to make informed decisions about their brain health, and we encourage you to share your experiences, insights, and questions in the comments section below.

Join our vibrant community of like-minded individuals passionate about optimizing their cognitive performance and well-being, and stay tuned for more in-depth articles, guides, and podcasts designed to help you navigate the fascinating world of nootropics.


1[Ito I, Tanabe S, Kohda A, Sugiyama H]. Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. [J Physiol]. [1990];424:533-543. doi: 10.1113/jphysiol.1990.sp018081.

2[Pizzi M, Fallacara C, Arrighi V, Memo M, Spano PF]. Attenuation of excitatory amino acid toxicity by metabotropic glutamate receptor agonists and aniracetam in primary cultures of cerebellar granule cells. [J Neurochem]. [1993];61(2):683-689. doi: 10.1111/j.1471-4159.1993.tb02177.x.

3[Toide K]. Effects of aniracetam on one-trial passive avoidance tests and cholinergic neurons in discrete brain regions of rats. [Arch Int Pharmacodyn Ther]. [1990];307:117-126.

4[Vaglenova J, Pandiella N, Wijayawardhane N, et al]. Aniracetam reversed learning and memory deficits following prenatal ethanol exposure by modulating functions of synaptic AMPA receptors. [Neuropsychopharmacology]. [2008];33(5):1071-1083. doi: 10.1038/sj.npp.1301496.

5[Nakamura K, Kurasawa M]. Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. [Eur J Pharmacol]. [2001];420(1):33-43. doi: 10.1016/s0014-2999(01)01005-6.

6[Koliaki CC, Messini C, Tsolaki M]. Clinical efficacy of aniracetam, either as monotherapy or combined with cholinesterase inhibitors, in patients with cognitive impairment: a comparative open study. [CNS Neurosci Ther]. [2012];18(4):302-312. doi: 10.1111/j.1755-5949.2010.00244.x.

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Erik Abramowitz is a certified Nutritional Therapy Practitioner (NTP), Naturopathic Doctoral student, health coach, and father. He is the primary content creator for and the host of the Holistic Nootropics Podcast.