Best Nootropics For Sex Drive And Libido

Last Updated:
Medically reviewed by Dr. Harshi Dhingra

Key Information

Nootropics are substances that enhance cognitive function

They can improve memory, focus, mood, creativity, and motivation.

Nootropics can also affect sex hormones and neurotransmitters

They can lower stress, increase dopamine, boost testosterone, and improve blood flow.

Nootropics can help with sexual desire, arousal, and satisfaction

They can enhance libido, stamina, erectile function, orgasm, and fertility.

Nootropics are natural, safe, and effective

They are derived from plants, herbs, amino acids, vitamins, and minerals. They have few or no side effects.

Affiliate Disclosure: Holistic Nootropics may earn affiliate commissions if you purchase through the links on this page. Here's how it works.

Hey good lookin’, welcome to my roundup of the best nootropics for sex drive and libido

If you want to boost your libido naturally, the good news is that many nootropics and biohacks are clinically proven to help.

As a fella in my 40’s, I’ve had much success using different nootropics, supplements, and lifestyle hacks in my own life to fend off the dreaded sexual slump that comes with age.  (not to brag) (ok I’m kind of bragging)

In fact, there is a lot of good science backing up the use of each item discussed in this article highlighting benefits like boosts in sexual desire, performance, and fertility with few if any side effects.

I know as I’ve spent many hours combing through the scientific literature, along with personally testing many of the following products.

So if you’re ready to discover some of the best nootropics for libido and sex drive enhancement, take a scroll further down the page and enjoy!

Biohack Your Brainpower

Stay ahead with our newsletter: cutting-edge biohacking tips and the latest in nootropics, all in one place.

The Best For Nootropics For Sex Drive And Libido – Quick Answers

Testo Lab Pro #1

Testo Lab Pro

Natural Testosterone-Boosting Blend
Check PriceBuy 3 Months, Get 1 Free
Mucuna Pruriens #2

Mucuna Pruriens

Dopamine, Libido Enhancer
Phosphatidylserine by Nootropics Depot #3

Phosphatidylserine by Nootropics Depot

Lower Stress Hormones = More Sex Hormones
Check PriceGet 5% off entire order w/ code HOLISTICNOOTROPICS
Blood Sugar Breakthrough by Bioptimizers #4

Blood Sugar Breakthrough by Bioptimizers

Better Blood Sugar For Optimal Hormone Production
Check PriceSave add’l 10% w. code HOLISTICNOOTROPICS @ checkout
NooCube #5


All-Natural Nootropics Proven To Boost Libido
Check PriceGet 20% off three bottles
L-Arginine by Nootropics Depot #6

L-Arginine by Nootropics Depot

Boost Blood Flow To Special Parts
Mind Lab Pro #7

Mind Lab Pro

Science-backed nutrition for your brain
Check PriceBuy 3 bottles, get 1 free with our links
Cordyceps Mushroom Powder by Freshcap #8

Cordyceps Mushroom Powder by Freshcap

The Mushroom for Energy
Magnesium Breakthrough #9

Magnesium Breakthrough

Crucial Mineral For Sexual Health
Check PriceUse code: HOLISTICNOOTROPICS to save 10%
Curcumin - Nootropics Depot #10

Curcumin – Nootropics Depot

Nature's Tylenol
Acetyl L-Carnitine (ALCAR) by Nootropics Depot #11

Acetyl L-Carnitine (ALCAR) by Nootropics Depot

Clinically Proven To Boost Performance
Check PriceGet 5% off entire order w/ code HOLISTICNOOTROPICS
CZTL Methylene Blue #12

CZTL Methylene Blue

Energy Crystals: CZTL Methylene Blue
Check PriceFree Tracked Shipping
Lipo NMN by Renue by Science #13

Lipo NMN by Renue by Science

Enhance Hormones @ Cellular Level

Hormones Are Holistic

It’s important to remember that libido is 100% driven by hormones, and hormones are best optimized by holistic practices.

While it’s tempting to want a “quick fix”, the truth is that if you’re in your 20’s, 30’s, or 40’s a low sex drive, could be a sign that you have a more foundational issue that must be addressed.

These are your sexual prime years, and if you’re falling flat in the bedroom, you need a relentless focus on boosting your body’s ability to make sex hormones like testosterone (men) and estrogen (women).

Nootropics for sex and libido - Needs more images

In short, no sex hormones = no sex drive.

This comes from your endocrine system, and nowadays many people deal with slight to severe endocrine disorders… mainly caused by excessive stress and inflammation.

If you’re one of the many people who want natural solutions for these issues there are 2 crucial components you must address:

Metabolism and Gut Health

Nootropics, in conjunction with probiotics and metabolism-friendly nutrients, is the ultimate formula for optimizing libido and overall sexual performance.

The following article lists some biologically proven, safe hacks that can turn your body into a sex machine.

Some nootropics may increase desire and libido.

Hacking The Endocrine System

The endocrine system is like a finely tuned orchestra.

Each organ is an instrument, the hormones are the notes, and the music is expressed in how you feel.

When your orchestra plays the hits, you feel unstoppable.

If even just one of the instruments stumbles and plays the wrong notes, the whole system falls apart, leaving you feeling flat, deflated, and unmotivated for love-making.

For your orchestra to play optimally, your metabolism and gut health must be on point.

That’s because metabolism dictates cellular functionality while gut health heavily influences inflammation and hormone production.

Many studies have demonstrated metabolic health1Adriana Maggi. Sex, metabolism and health Mol Metab. 2018 and gut microbial balance’s2 Ji-Hee Shin, et al. Serum level of sex steroid hormone is associated with diversity and profiles of human gut microbiome Res Microbiol. Jun-Aug 2019 role in sex hormone production.

The following biohacks will help you optimize these pathways for sustainable sex hormone production.

Blood Sugar Breakthrough

Mastering metabolism means regulating your blood sugar. The number one way to do this is through diet and lifestyle.

Following a low sugar, low processed food diet with regular exercise is half the battle.

Supplementing with specific, blood sugar-regulating nutrients is also essential.

There are many herbs, amino acids, and minerals that work great for this.

Fortunately, there is one product that includes many of them called Blood Sugar Breakthrough.

This powerful formula includes some of the most potent ingredients for regulating blood sugar including:

  • Biotin
  • Dihydroberberine
  • Chromium
  • Banabana
  • Bitter Melon

Lumen Metabolism Tracker

No matter what supplement or nootropic you take, if you don’t get your nutrition in check you’ll never get your metabolism straight.

One of the best tools to help you get your nutrition in check is the Lumen Metabolism Tracker.

It’s a small, easy-to-use, portable device that tells you if your body is burning carbohydrates or fat.

Getting this balance right is called metabolic flexibility, which is the gold standard of metabolism optimization.

Use this tracker throughout the day to get real-time data on how different foods, workouts, and sleep affect your metabolism.

Check out my full review of the LUMEN Metabolism Tracker or get it directly at the link above!


Having a diverse ecosystem of gut bacteria is crucial in optimal endocrine function.

These microbes influence the enteroendocrine cells within the gut lining that produce hormones that ultimately affect the function of the rest of the endocrine system3Alyce M. Martin. The Influence of the Gut Microbiome on Host Metabolism Through the Regulation of Gut Hormone Release Front Physiol. 2019.

Supplementing with probiotics is the most effective way to enhance microbial diversity in the gut.

Unfortunately, most probiotics are ineffective since they’re not designed to survive the harsh conditions of your stomach and digestive tract.

Megasporebiotic on the other hand is a medical-grade probiotic formula that includes 5 strains of spore-based microbes that are designed to survive your GI barrier and successfully colonize your gut.

Megaspore is the #1 recommended probiotic among functional medicine doctors and nutrition practitioners.

Check out my Full Review of Megasporebiotic or buy directly from the link above.

The Endocrine System and Libido

Sex drive and libido are controlled physiologically by your endocrine system.

The endocrine system is like a finely tuned orchestra composed of endocrine glands and hormone-producing tissues, hormones, and receptors.

Each gland is an instrument, the hormones are the notes, and the music is expressed in how you feel.4Carolyn Johnstone, Charles Hendry, Alistair Farley, Ella McLafferty. Endocrine System: Part 1 Nurs Stand. 2014

When your orchestra plays the hits, you feel unstoppable.

If even one of the instruments stumbles and plays the wrong notes, the whole system falls apart, making you feel flat.
… and so do your special love-making parts.

If even one part is off, the dysfunction cascades and sabotages the function of the organs downstream.

This means sex hormones are not made, and you don’t get that desire to get it on.

Read More: TestoLab Pro: Full Review

Sex Drive, Neurotransmitters, and The Brain

The brain plays a major role in your desire to have sex.

So much is happening at a biochemical level that can directly influence this desire.5Arthur L Burnett, Michael C Truss. Mediators of the Female Sexual Response: Pharmacotherapeutic Implications World J Urol. 2002

While plenty of plants and foods are touted for their aphrodisiac effects, understanding the interplay of neurotransmitters, hormones, and the nervous system can help you hack your sex drive.

Stress and Sex

It’s important to remember that your body is a 2 million-year-old organism that houses some incredibly intuitive machinery.

One great example is the balance of stress response and sex hormones.

Sex hormones like testosterone and estrogen are made in your adrenal glands at the direction of your HPA Axis.6S E WAXENBERG, M G DRELLICH, A M SUTHERLAND. The Role of Hormones in Human Behavior. I. Changes in Female Sexuality After Adrenalectomy J Clin Endocrinol Metab. 1959

The HPA Axis is your body’s internal stress response system and is always on the lookout.

It regulates your sympathetic (fight or flight) and parasympathetic (rest and digest) autonomic nervous systems.7Kamani Liyanarachchi, Richard Ross, Miguel Debono. Human Studies on Hypothalamo-Pituitary-Adrenal (HPA) Axis Best Pract Res Clin Endocrinol Metab. 2017

At any given time, your body is in one or the other of these nervous system states.  It cannot be both sympathetic and parasympathetic simultaneously.

When your body is in a panic, i.e., fight or flight, it makes stress hormones like cortisol and norepinephrine.

Sex hormones, however, are a product of a stress-free, parasympathetic state in the body.8Emma C. Hart, Nisha Charkoudian, and Virginia M. Miller. Sex, Hormones and Neuroeffector Mechanisms Acta Physiol (Oxf) 2012

Your body’s intrinsic response to stress will always prioritize making stress hormones over sex hormones.  This is known as the pregnenolone (or cortisol) steal.

When you think about our human evolution, this makes sense.  How can you want to get your groove on when your running from a tiger?

This response is still with us today and plays a huge role in much sexual dysfunction.

Understanding how to lower your stress response in favor of producing more sex hormones is the ultimate libido hack!

Read More: Why You Should Never Buy Nootropics From Amazon

Understanding The Natural Female Libido

Unlike men, women’s sexual desire comes from estrogen and testosterone’s interplay made in her ovaries.9Maurand Cappellettia and Kim Wallen. Increasing women’s sexual desire: The comparative effectiveness of estrogens and androgens Horm Behav. 2017

While testosterone plays into a woman’s libido, estrogen has an overwhelming influence.10]Lorraine Dennerstein, John Randolph, John Taffe, Emma Dudley, Henry Burger. Hormones, Mood, Sexuality, and the Menopausal Transition Fertil Steril. 2002

Many studies show that a woman’s interest in sex has a lot to do with her menstrual cycle timing and typically peaks midcycle around the time of ovulation.11S H Van Goozen, V M Wiegant, E Endert, F A Helmond, N E Van de Poll. Psychoendocrinological Assessment of the Menstrual Cycle: The Relationship Between Hormones, Sexuality, and Mood Mood, Arch Sex Behav.1997

Cortisol and stress-hormone production also plays an important role in sex drive.  These glucocorticoids can disrupt the production of estrogen, which can sabotage libido.12Fatma Ela Keskin, Hande Mefkure Özkaya, Mazhar Ortaç, Emre Salabaş, Ateş Kadıoğlu, and Pınar Kadıoğlu. Sexual function in women with Cushing’s Syndrome: A controlled study Turk J Urol. 2018

This makes sense since the body prioritizes survival with a stress response over reproduction.

For a woman to truly optimize her sex drive, she must optimize estrogen production, which requires lowering glucocorticoid response.

This is best done by lowering stress and managing the HPA Axis.

Understanding The Natural Male Libido

Testosterone levels play a large role in maintaining a healthy sex drive for menThe male libido is, of course, a complicated system, but one of the primary issues is testosterone.

Testosterone is a hormone that regulates sex drive, desire, and sperm production.

It also plays a significant role in other important health aspects like muscle growth, sleep, and mood.

Like estrogen, testosterone production is highly dependent on the HPA axis function and keeping the body’s stress response low.13George N. Nassar; Fernando Raudales; Stephen W. Leslie.. Physiology, Testosterone StatPearls. 2020

High stress-hormone production due to physical and emotional stress can sap the body of its ability to produce testosterone.

Low testosterone can be one source of sexual issues. Fortunately, some nootropic remedies may give you the boost you need.

Sex Hormones and Gut Health

New microbiome research reveals a connection between gut bacterial diversity and sex hormones.14Ji-Hee Shin , Young-Hee Park, Minju Sim, Seong-Ah Kim, Hyojee Joung, Dong-Mi Shin. Serum level of sex steroid hormone is associated with diversity and profiles of human gut microbiome Res Microbiol. Jun-Aug 2019

Having a gut filled with diverse species of bacteria is proving to be beneficial for overall health. It has been shown to influence both testosterone in men and estrogen in women positively.

A good way to get a diverse microbiome is to eat a diverse diet made up of whole-foods.  This includes organic fruits, vegetables, meat from pasture-raised animals, and minimal fried foods.

Probiotics are also a great way to add diversity to your microbiome.

The point of a good probiotic is to supply your gut with bacterial strains that you can’t get from food.  This includes fermented foods.

Most people are lacking many beneficial bacterial strains due to a history of antibiotics, pharmaceuticals, and poor diet.

A good probiotic will reseed your gut with good bacteria, which can help boost sex hormone production.  Check out my recommendation below.

Best Nootropic Supplements for Sex Drive and Libido

Natural Testosterone-Boosting Blend

Testo Lab Pro

Testo Lab Pro
Check PriceBuy 3 Months, Get 1 Free
Check PriceBuy 3 Months, Get 1 Free
  • Increase your masculine vitality and energy

  • Reduce sexual dysfunction due to high blood sugar levels

  • Improve your sex drive and libido

  • Regain the ability to have orgasms

  • Enjoy a better quality of life

TestoLab Pro is our top choice to naturally enhance testosterone.

Made from all-natural ingredients, clinically proven to boost sexual vitality and desire while enhancing strength, muscle pump, motivation, and mental clarity like  Ashwagandha (KSM-66), D-Aspartic Acid, and Mucuna Pruriens Extract.

The included Luteolin is a natural testosterone preservation system that keeps your manufactured T from being hijacked and converted into estrogen.

There’s also added Zinc, Magnesium, and Vitamin D to help keep your hormone production pathways optimized for proper nutrient synthesis while at the same time reducing stress hormones.


  • Natural ingredients to raise testosterone
  • Can increase sex drive, semen volume, erectile function, and sperm count
  • Helps fat loss, belly fat reduction, man-boob reduction, and more
  • Cognition, confidence, and mindset


  • Not as potent as TRT
  • Only available on the official website

The Magic Velvet Bean

Mucuna Pruriens

  • Contains levodopa (L-dopa), a precursor to the neurotransmitter dopamine

  • Improves mood, increased motivation, and enhanced cognitive function

  • Can also improve cognitive function and memory.

Mucuna pruriens is a natural supplement that has been used in Ayurvedic medicine to reduce stress, anxiety, improve focus, boost libido and mood.

Mucuna pruriens is a type of adaptogen that helps your body better handle stress. This plant contains high levels of L-dopa, which is the precursor to dopamine. Dopamine is a brain chemical that plays a major role in motivation, pleasure, and emotions. If you don’t have enough dopamine, you might feel tired, unfocused, and depressed.

In 2014 researchers studied the effect of a plant called mucuna pruriens on rats who had anxiety. They used three different experimental models and gave the rats this plant for a long time. The results showed that the plant worked to reduce anxiety in each of the models.

Mucuna also shows promise in treating stress and depression. However, it is possible that giving mucuna to people who suffer from depression caused by low serotonin levels could make their depression worse. That’s because dopamine in large enough doses may interfere with the production of serotonin.

Some people with ADHD tendencies may find that mucuna helps them stay on task. One study found that L-dopa was as effective as methylphenidate (Ritalin) in treating ADHD symptoms. Another study found that L-dopa improved working memory and reaction time in adults with ADHD.

L-dopa is also a key neurotransmitter involved in sexual desire and arousal, and a recent clinical trial showed that supplementation with Mucuna Pruriens significantly improved sexual function in men with low libido.


  • Mucuna Pruriens has been clinically proven to help men with fertility
  • Shown to be effective in treating many conditions such as Parkinson’s disease, depression, and anxiety.
  • Has been used in traditional Ayurvedic medicine for centuries
  • Available in powder and capsule form
  • All-Natural


  • One of the most common side effects associated with Mucuna Pruriens is nausea. This can be caused by the high levels of L-dopa in the supplement, which can sometimes upset the stomach.

#1 Blood Sugar Support Supplement

Blood Sugar Breakthrough by Bioptimizers

Blood Sugar Breakthrough by Bioptimizers
Shop NowSave add’l 10% w. code HOLISTICNOOTROPICS @ checkout
Shop NowSave add’l 10% w. code HOLISTICNOOTROPICS @ checkout
  • Reduce sexual dysfunction due to high blood sugar levels

  • Regain the ability to have orgasms

  • Enjoy a better quality of life


  • Contains natural ingredients that have been clinically proven to help lower blood sugar levels
  • Has been shown to help people lose weight
  • comes with a money-back guarantee, so you can feel confident that you’re not wasting your money if it doesn’t work for you
  • Produced by BiOptimizers, one of the most trusted names in the Supplement Industry


  • Can be a bit pricey
  • Encapsulation includes magnesium stearate, and silicon dioxide (not toxic at low levels, but not 100% clean)

Uncontrolled blood glucose levels has been identified as one of the major causes of erectile dysfunction, impotence and lowered sex drive among men.

This is especially true among diabetics and prediabetics1Giovanni Corona , Giulia Rastrelli, Valdo Ricca, Emmanuele A Jannini, Linda Vignozzi, Matteo Monami, Alessandra Sforza, Gianni Forti, Edoardo Mannucci, Mario Maggi, Risk factors associated with primary and secondary reduced libido in male patients with sexual dysfunction, J Sex Med. 2013

Excessively high blood sugar levels negatively alter several body systems such as the circulatory, nervous, and the endocrine system which in turn affects the sexual drive of an individual. 2Kelli L. Copeland, BA, Jeanette S. Brown, MD, Jennifer M. Creasman, MSPH, Stephen K. Van Den Eeden, PhD, Leslee L. Subak, MD, David H. Thom, MD, PhD, Assiamira Ferrara, MD, PhD,and Alison J. Huang, MD, MAS, Diabetes Mellitus and Sexual Function in Middle-Aged and Older Women, Obstet Gynecol. 20133Author(s), Sexual dysfunctions in patients with diabetes: a study from Iran, Reprod Biol Endocrinol. 2010

Blood Sugar Breakthrough effectively treats this metabolism-libido pathway as it’s formula is designed to optimize blood glucose levels and overall metabolism, which will ultimately boost your sex drive and sexual performance.

Maximize your mental performance for peak productivity


Shop NowGet 20% off three bottles
Shop NowGet 20% off three bottles
  • Better overall mental health and well-being from ingredients can lead to increased sex drive

  • Lower stress for increased sex hormone production

  • Boosts sexual desire, motivation, physical responsiveness, and energy


  • Preformulated for easy access to essential nootropics
  • Best value for nootropic cognitive enhancement
  • All-natural ingredients with no fillers/preservatives
  • Includes B-vitamins for enhanced metabolism


  • Some ingredients may be underdosed for specific nootropic therapy

#1 Stress Management Nootropic

Phosphatidylserine by Nootropics Depot

Phosphatidylserine by Nootropics Depot
Check PriceGet 5% off entire order w/ code HOLISTICNOOTROPICS
Check PriceGet 5% off entire order w/ code HOLISTICNOOTROPICS
  • Phosphatidylserine is an abundant phospholipid in the brain

  • Shown to improve cognitive function in people with age-related cognitive decline

  • Help reduce inflammation and protect nerve cells from damage

  • Crucial in cellular membrane function and protection

Phosphatidylserine (PS) is a phospholipid molecule that is abundant in the brain. It is a major component of cell membranes and is involved in cell signaling. PS supplements have been shown to have nootropic effects, including improved memory, concentration, and mental clarity.

Additionally, PS has also been shown to improve cognitive function in people with age-related cognitive decline. The exact mechanisms by which PS exerts its nootropic effects are not fully understood, but it is thought to work by modulating neurotransmitter levels and improving neuronal membrane fluidity.

No matter how it works, though, there’s no doubt that PS supplements can have a positive impact on cognitive function. So if you’re looking for a way to boost your brainpower, consider giving PS a try!

Science-backed nutrition for your brain

Mind Lab Pro

Mind Lab Pro
Shop NowBuy 3 bottles, get 1 free with our links
Shop NowBuy 3 bottles, get 1 free with our links
  • Works synergistically to enhance sex drive and performance

  • Enhances mood for an even more potent sexual experience

  • 11 nootropic ingredients work together to produce the best results


  • Proven to boost overall cognitive performance including memory, focus, mood, creativity, motivation, and overall well-being.
  • Potent blend of all-natural nootropics, herbs, amino acids, vitamins, and minerals.
  • Good for experienced biohackers and those new to nootropics.
  • Caffeine Free
  • No artificial fillers or toxic preservatives
  • Affordable Price, money back guarantee


  • Ingredients are lower dosed.

Mind Lab Pro’s 11 nootropic ingredients work synergistically to enhance sex drive and performance.

This formula includes adaptogens and amino acids that lower your body’s stress response, boosting sex hormone production.

You also get potent nootropics and amino acids that keep your mood right and your brain thinking sexy thoughts.

The included B-vitamin co-factors help optimize absorbability.

The supplements themselves are 3rd party tested and free of excess fillers and toxic ingredients.

I love this stack for nootropic newbies and experienced nootropic users alike.

Most Bio-Available l-Arginine

L-Arginine by Nootropics Depot

  • Highly effective supplement for enhanced athletic performance.

  • Improves blood flow for lower blood pressure and better blood delivery to the brain

  • May help improve memory and learning

  • Crucial component for building proteins and ridding the body of toxic ammonia

  • Potential anti-aging, longevity benefits

Arginine Alpha-Ketoglutarate (AAKG) 2:1 is a beneficial supplement that can help improve cognitive health. AAKG helps to increase nitric oxide production in the brain, which has been found to improve blood flow and oxygenation to the brain. This increased oxygen supply allows for improved communication between neurons and enhanced cognition. Additionally, AAKG has been found to increase energy levels, which can help reduce mental fatigue and enhance focus.4Bibek Gyanwali, et al. Alpha-Ketoglutarate dietary supplementation to improve health in humans
Trends in Endocrinology & Metabolism. 2022

Furthermore, AAKG has been linked with improved memory formation due to its ability to increase the formation of glutamate receptors in the brain. Glutamate is an important neurotransmitter that helps regulate memory formation and recall. Finally, AAKG may also benefit those with mild cognitive impairment as it helps reduce neuronal damage caused by excessive oxidation.

Overall, Arginine Alpha-Ketoglutarate (AAKG) 2:1 is beneficial for cognitive health as it increases nitric oxide production and oxygenation in the brain, boosts energy levels, enhances memory formation and recall, and reduces oxidative damage from neurons.

Improve Sexual Performance in Men and Women

Cordyceps Mushroom Powder by Freshcap

  • Enhance stamina and energy levels

  • Increase libido, sperm production in men

  • A natural alternative to pharmaceutical drugs


  • Available in capsules and powder form
  • Can protect against health problems like asthma, depression, diabetes, fatigue, high cholesterol, and upper respiratory tract infections.
  • Has been shown to improve athletic performance and reduce fatigue.
  • All-natural


  • Quality cordyceps can be quite expensive and hard to find

Cordyceps is a medicinal mushroom, which has been used therapeutically on the Asian continent for centuries.

Consuming cordyceps just a few times a week has been shown to enhance vigor and vitality which ultimately leads to better sex drive and libido.5Kanitta Jiraungkoorskul and Wannee Jiraungkoorskul, Review of Naturopathy of Medical Mushroom, Ophiocordyceps Sinensis, in Sexual Dysfunction, Pharmacogn Rev. 2016

It offers an organic and natural substitute to other pharmaceutical drugs used to enhance libido.6Jin Xu, Ying Huang, Xiang-Xiang Chen, Shuai-Chao Zheng, Peng Chen, Ming-He Mo, The Mechanisms of Pharmacological Activities of Ophiocordyceps sinensis Fungi, Phytother Res. 2016

This mushroom has been found to promote sperm production, enhance stamina, improve erectile function, cure male impotence, and upsurge sexual desire in both men and women.7Kanitta Jiraungkoorskul , Wannee Jiraungkoorskul, Review of Naturopathy of Medical Mushroom, Ophiocordyceps Sinensis, in Sexual Dysfunction, Pharmacogn Rev. 2016

Freshcap Mushrooms provide the highest percentage of beta glucans and fruiting body nutrients, making this mushroom product my preferred choice for Cordyceps.

#1 Magnesium Product

Magnesium Breakthrough

Magnesium Breakthrough
Shop NowUse code: HOLISTICNOOTROPICS to save 10%
Shop NowUse code: HOLISTICNOOTROPICS to save 10%
  • Supports muscle growth

  • Improves sex drive and libido

  • Enhances fertility

  • Helps balance hormones


  • Includes the 7 most effective forms of magnesium
  • Highly credible manufacturer
  • No added fillers, preservatives, or unnecessary ingredients
  • Free shipping and discounts are available


  • Underdosed for specific magnesium type you may want

Magnesium is crucial in production of various vital hormones. Researchers have observed and linked this mineral with muscle growth, sex drive, testosterone level and production of gametes i.e., sperms in males and eggs in females.8ViskiJ. SzöllosiA. S. KissA. Csikkel-Szolnoki, Effects of Magnesium on Spermiogenesis, Kluwer Academic Publishers. 1997
Hence, it has been proven to maximize sex drive and libido.9Vedat Cinar, Yahya Polat, Abdulkerim Kasim Baltaci & Rasim Mogulkoc , Effects of Magnesium Supplementation on Testosterone Levels of Athletes and Sedentary Subjects at Rest and after Exhaustion, Biological Trace Element Research. 2010

Literature suggests that uptake of dietary magnesium regularizes the levels of DHEA (dehydroepiandrosterone), boosts testosterone levels, ameliorate symptoms of premature ejaculation and erectile dysfunction, enhance libido, and also aids with conception and fertility.10David A. Kalmbach PhD, J. Todd Arnedt PhD Vivek Pillai PhD Jeffrey A. Ciesla PhDThe Impact of Sleep on Female Sexual Response and Behavior: A Pilot Study, Wiley Online Library. 201911Rachel Leproult, PhD; Eve Van Cauter, PhD, Effect of 1 Week of Sleep Restriction on Testosterone Levels in Young Healthy Men, JAMA. 2011

One of the main components of Magnesium Breakthrough is magnesium citrate. This form of magnesium is particularly recommended for overall reproductive health and wellness in both men and women.

Nature’s Tylenol

Curcumin – Nootropics Depot

  • Nature’s powerful anti-inflammatory compound

  • Delivers potent physical and cognitive benefits

  • Lower body inflammation = Stronger brain

  • Cognitive benefits include neuroprotection, better memory, faster brain processing speed, reduced brain fog

Curcumin is a compound found in turmeric that has many potential health benefits. A curcumin supplement can provide physical and cognitive benefits due to its antioxidant, anti-inflammatory, and neuroprotective properties12Susan J. Hewlings and Douglas S. Kalman. Curcumin: A Review of Its’ Effects on Human Health
Foods. 2017


The exact mechanism of how curcumin works in the body is still not fully understood. Still, research has shown that it affects various pathways and processes related to inflammation and oxidative stress.

Curcumin modulates the activity of certain enzymes involved in the inflammatory response, such as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX).

It also binds to cell receptors that control inflammation, including nuclear factor kappa B (NF-κB).

Furthermore, curcumin acts as an antioxidant by scavenging damaging molecules known as reactive oxygen species (ROS) which cause oxidative damage.

These anti-inflammatory and antioxidant effects are thought to be responsible for the potential physical and cognitive benefits of taking a curcumin supplement, such as the reduced risk of heart disease or improved brain function.

Numerous studies have confirmed curcumin’s cognitive benefits ranging from neuroprotection to improvements in memory and brain processing speed.13I-Chen Tsai, et al. The Effect of Curcumin Differs on Individual Cognitive Domains across Different Patient Populations: A Systematic Review and Meta-Analysis
Pharmaceuticals (Basel)
. 2021

However, further research is needed to understand how curcumin works in the body and its potential therapeutic applications

Boost energy levels and athletic performance

Acetyl L-Carnitine (ALCAR) by Nootropics Depot

Acetyl L-Carnitine (ALCAR) by Nootropics Depot
Check PriceGet 5% off entire order w/ code HOLISTICNOOTROPICS
Check PriceGet 5% off entire order w/ code HOLISTICNOOTROPICS
  • Improve cognitive function

  • Protect the brain from damage

  • Boost energy levels

  • Enhance athletic performance

Acetyl L-Carnitine (ALCAR) is a supplement that has many potential benefits. It is most commonly known for its nootropic effects, which means that it can help to improve cognitive function.

ALCAR is thought to work by increasing levels of acetylcholine, a neurotransmitter that is essential for memory and learning.

ALCAR has been shown to protect the brain from damage caused by free radicals, and it may even help to reverse some of the cognitive declines that occurs with age.

In addition to its nootropic effects, ALCAR has also been shown to boost energy levels and athletic performance. This is thought to be due to its ability to increase levels of carnitine, an amino acid that helps the body to burn fat for fuel.

Additionally, ALCAR has been shown to improve heart health by reducing oxidative stress and improving blood flow.

Overall, ALCAR is a safe and effective supplement that offers many potential benefits.

Energy Crystals: CZTL Methylene Blue

CZTL Methylene Blue

CZTL Methylene Blue
View OfferFree Tracked Shipping
View OfferFree Tracked Shipping
  • Fast Effects

  • Clear Energy

  • Improves Mood

CZTL methylene blue provides a short burst of stimulation, motivation, mood lift, and mental clarity by improving oxygen flow and electron transport in the brain and body. The small crystals dissolve completely with no residue or particles. Effects are felt within 5 minutes but last 30 minutes max. Despite the esoteric name suggesting synthetic origin, CZTL is simply ultra-pure methylene blue.


  • Occasional Use
  • No Fillers
  • Motivation on Demand


  • Potential for Serotonin Syndrome
  • Undefined Regulatory Status
  • Not for Daily Use
  • Can Stain Skin and Urine Blue Temporarily
  • Terminal Half-life Under 2 hours

#1 NMN Capsule for Weight Loss, Anti-Aging, and Energy

Lipo NMN by Renue by Science

  • Special formulation is easily absorbed and utilized by the body

  • Increases energy levels, cognitive function, and overall health in people with low NAD+ levels.

  • Can help improve mitochondrial function and energy levels

  • Improves skin health and appearance

  • Affiliate Disclosure: Holistic Nootropics is an affiliate for Renue By Science and will earn commissions if you purchase through these links.

Renue By Science Lipo NMN is my #1 choice for NMN supplements.

Not only do their products provide you with a potent dose of NMN, which is known to help improve cellular function and protect your DNA, but they have the biggest selection of NMN to choose from.

They offer pure NMN powder and tablets, liposomal NMN, NMN sublingual delivery, NMN nasal spray, and NMN blended with other anti-aging nutrients.

Each of these products are guaranteed to give you the NAD+ boost you need to feel more energetic and youthful.

Be sure to check out Renue By Science NMN customer reviews below!

“I’ve been using the sublingual NMN for the past year and wouldn’t do without it! From the first time I used it, to each time I use it, I can feel an uptick in energy and notice that my immune system seems to function better overall. I haven’t been sick since we started using it! I originally tried NMN supplements because I had come down with a really bad flu last February (not Covid) and was having a hard time recovering. While I was sick I read Dr. David Sinclair’s book, Lifespan, and decided to try using NMN. Wow, what a difference it made in my recovery! I got better so quickly after I started taking the supplements.

During my recovery, I took four of the sublingual tablets/day to boost my DNA repair mechanisms, and now for maintenance, I take the recommended 2/day. I’ve also tried both the LSG NMN and the SLC NMN and have found both to be equally as effective. I like switching the delivery mechanism for the NMN periodically to get the best response from my body. ” 

– Jesse K.

“The darkening of my hair has been noticeable over the last 3 months or so. I take RBS Liposomal NMN and Fisetin amongst a range of other supplements.

The improvement to my facial skin & back of my hands is absolutely associated with the Renue applications. I had noticed it but when other people started commenting I felt that I had something more concrete to contribute. So in summary this is a remarkable result by any standards.” 

– Lloyd D.

“I have spent most of my life struggling with chronic pain and disease. I was pleased to not have any stimulating effects, but rather subtle yet very powerful changes after using nmn for only a couple of weeks. I notice deeper sleep, better recovery, and more strength during heavy lifts. I also noticed subtle mood changes, like not having that sort of blah feeling when it’s dark, gray, and raining outside.

I have since tried more products by Renue by Science and have noticed benefits with each and every one. Their formulations are excellent and the quality of their products is Dependable through and through.” 

– Rebekah F.

Comparison Of The Different Renue By Science NMN Products

Wrapping Up

While these are the most widely used supplements for libido, this field is ever-expanding (pun intended).

What Nootropics are you using for boosting your sex drive? Lets us know in the comments. (I know we’re all adults here, but please try to keep it clean!)


Biohack Your Brainpower

Stay ahead with our newsletter: cutting-edge biohacking tips and the latest in nootropics, all in one place.
Photo of author


Erik Abramowitz is a certified Nutritional Therapy Practitioner (NTP), Naturopathic Doctoral student, health coach, and father. He is the primary content creator for and the host of the Holistic Nootropics Podcast.

Leave a Comment