Nootropics for sex and libido - Needs more images

Best Nootropics For Sex Drive And Libido

Medically reviewed by Dr. Harshi Dhingra — Written by Erik Levi, FNTP — Updated on July 5, 2021


  • Nootropics can help boost your mind’s desire for sex through neurotransmitter optimization.

  • Biohacking your metabolism and gut health are the most potent ways to boost sex-hormone production.

  • Your libido is dictated by your endocrine system’s ability to make sex hormones.

  • The combination of biohacking and nootropics can significantly boost your sex drive and performance.

Nootropics for sex and libido -

If you’re looking to naturally boost your libido there are many nootropics and biohacks that are clinically proven to help.

I’ve had much success employing some of these techniques in my own life.

As a male in my late 30’s I’ve withstood the dreaded sexual slump that comes with age.  (not to brag)

But, to be honest, it’s not easy.

While it’s tempting to want a “quick fix”, the truth is that if you’re in your 20’s, 30’s, or 40’s a low sex drive, could be a sign that you have a more foundational issue that must be addressed.

These are your sexual prime years, and if you’re falling flat in the bedroom, you need a relentless focus on boosting your body’s ability to make sex hormones like testosterone (men) and estrogen (women).

Nootropics for sex and libido - Needs more images

In short, no sex hormones = no sex drive.

This comes from your endocrine system and nowadays many people deal with slight to severe endocrine disorders… mostly caused by excessive stress and inflammation.

If you’re one of the many people who want natural solutions for these issues there are 2 crucial components you must address:

Metabolism and Gut Health

Nootropics in conjunction with probiotics and metabolism-friendly nutrients is the ultimate formula for optimizing libido and overall sexual performance.

The following article lists some biologically proven, safe hacks that can turn your body into a sex-machine.


Valeria BoltnevaSome nootropics may increase desire and libido.

What Are The Best For Nootropics For Sex Drive And Libido - Quick Answers

Blood Sugar BreakthroughStabilizes and promotes healthy blood sugar levelsLearn More
Magnesium#1 Magnesium ProductLearn More
Testo Lab ProNatural Testosterone-Boosting Blend Learn More
A staple in Eastern medicineLearn More
Mind Lab Pro#1 Nootropic For BeginnersLearn More
Cordyceps MushroomLearn More
Pine Bark ExtractAll natural ADHD remedyLearn More
Mucuna PruriensNatural dopamineLearn More
AshwagandhaTraditional herb with potent relaxing effectsLearn More
Alpha-GPCGreat source of choline that works well in nootropic stacksLearn More

Hacking The Endocrine System

The endocrine system is like a finely tuned orchestra.

Each organ is an instrument, the hormones are the notes, and the music is expressed in how you feel.

When your orchestra plays the hits, you feel unstoppable.

If even just one of the instruments stumbles and plays the wrong notes, the whole system falls apart, leaving you feeling flat, deflated, and unmotivated for love-making.

For your orchestra to play optimally, your metabolism and gut health must be on point.

That’s because metabolism dictates cellular functionality while gut health heavily influences inflammation and hormone production.

Many studies have demonstrated metabolic health1Adriana Maggi. Sex, metabolism and health, Mol Metab. 2018 and gut microbial balance’s2 Ji-Hee Shin, et al. Serum level of sex steroid hormone is associated with diversity and profiles of human gut microbiome, Res Microbiol. Jun-Aug 2019 role in sex hormone production.

The following biohacks will help you optimize these pathways for sustainable sex hormone production.

Blood Sugar Breakthrough

Mastering metabolism means regulating your blood sugar. The number one way to do this is through diet and lifestyle.

Following a low sugar, low processed food diet with regular exercise is half the battle.

Supplementing with specific, blood sugar-regulating nutrients is also essential.

There are many herbs, amino acids, and minerals that work great for this.

Fortunately, there is one product that includes many of them called Blood Sugar Breakthrough.

This powerful formula includes some of the most potent ingredients for regulating blood sugar including:

  • Biotin
  • Dihydroberberine
  • Chromium
  • Banabana
  • Bitter Melon
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  • Better Metabolism
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  • Reduce Stress and Anxiety

Blood Sugar


Lumen Metabolism Tracker

No matter what supplement or nootropic you take, if you don’t get your nutrition in check you’ll never get your metabolism straight.

One of the best tools to help you get your nutrition in check is the Lumen Metabolism Tracker.

It’s a small, easy-to-use, portable device that tells you if your body is burning carbohydrates or fat.

Getting this balance right is called metabolic flexibility, which is the gold standard of metabolism optimization.

Use this tracker throughout the day to get real-time data on how different foods, workouts, and sleep affect your metabolism.

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Having a diverse ecosystem of gut bacteria is crucial in optimal endocrine function.

These microbes influence the enteroendocrine cells within the gut lining that produce hormones that ultimately affect the function of the rest of the endocrine system3Alyce M. Martin. The Influence of the Gut Microbiome on Host Metabolism Through the Regulation of Gut Hormone Release, Front Physiol. 2019 .

Supplementing with probiotics is the most effective way to enhance microbial diversity in the gut.

Unfortunately, most probiotics are ineffective since they’re not designed to survive the harsh conditions of your stomach and digestive tract.

Megasporebiotic on the other hand is a medical-grade probiotic formula that includes 5 strains of spore-based microbes that are designed to survive your GI barrier and successfully colonize your gut.

Megaspore is the #1 recommended probiotic among functional medicine doctors and nutrition practitioners.

  • Spore-Based Probiotic 
  • Survives Stomach Acid
  • Fights Gut Infections
  • Full Gut Healing
  • Less Inflammation
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The Endocrine System and Libido

Sex drive and libido are controlled physiologically by your endocrine system.

The endocrine system is like a finely tuned orchestra composed of endocrine glands along with hormone-producing tissues, hormones, and hormone receptors.

Each gland is an instrument, the hormones are the notes, and the music is expressed in how you feel.4Carolyn Johnstone, Charles Hendry, Alistair Farley, Ella McLafferty. Endocrine System: Part 1, Nurs Stand. 2014

When your orchestra plays the hits, you feel unstoppable.

If even just one of the instruments stumbles and plays the wrong notes, the whole system falls apart, and you feel flat.
… and so do your special love-making parts.

If even one part is off, the dysfunction cascades and sabotages the function of the organs downstream.

This means sex hormones are not made, and you don’t get that desire to get it on.

Read More: TestoLab Pro: Full Review

Sex Drive, Neurotransmitters, and The Brain

The brain plays a major role in your desire to have sex.

There is so much happening at a biochemical level that can directly influence this desire.5Arthur L Burnett, Michael C Truss. Mediators of the Female Sexual Response: Pharmacotherapeutic Implications, World J Urol. 2002

While there are plenty of plants and foods touted for their aphrodisiac effects, understanding the interplay of neurotransmitters, hormones, and the nervous system can potentially help you hack your sex drive.

Stress and Sex

It’s important to remember that your body is a 2 million-year-old organism that houses some incredibly intuitive machinery.

One great example is the balance of stress response and sex hormones.

Sex hormones like testosterone and estrogen are made in your adrenal glands at the direction of your HPA Axis.6S E WAXENBERG, M G DRELLICH, A M SUTHERLAND. The Role of Hormones in Human Behavior. I. Changes in Female Sexuality After Adrenalectomy, J Clin Endocrinol Metab. 1959

The HPA Axis is your body’s internal stress response system and is always on the lookout.

It regulates your sympathetic (fight or flight) and parasympathetic (rest and digest) autonomic nervous systems.7Kamani Liyanarachchi, Richard Ross, Miguel Debono. Human Studies on Hypothalamo-Pituitary-Adrenal (HPA) Axis, Best Pract Res Clin Endocrinol Metab. 2017

At any given time, your body is in one or the other of these nervous system states.  It cannot be both sympathetic and parasympathetic simultaneously.

When your body is in a panic, i.e., fight or flight, it makes stress hormones like cortisol and norepinephrine.

Sex hormones, however, are a product of a stress-free, parasympathetic state in the body.8Emma C. Hart, Nisha Charkoudian, and Virginia M. Miller. Sex, Hormones and Neuroeffector Mechanisms, Acta Physiol (Oxf) 2012

Your body’s intrinsic response to stress will always prioritize making stress hormones over sex hormones.  This is known as the pregnenolone (or cortisol) steal.

When you think about our human evolution, this makes sense.  How can you want to get your groove on when your running from a tiger?

This response is still with us today and plays a huge role in much sexual dysfunction.

Understanding how to lower your stress response in favor of producing more sex hormones is the ultimate libido hack!

Read More: Why You Should Never Buy Nootropics From Amazon

  • 11 All-Natural Nootropics 
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  • More Focus and Concentration
  • Improve Memory
  • Stress Reduction

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Understanding The Natural Female Libido

Unlike men, women’s sexual desire comes from estrogen and testosterone’s interplay made in her ovaries.9Maurand Cappellettia and Kim Wallen. Increasing women’s sexual desire: The comparative effectiveness of estrogens and androgens, Horm Behav. 2017

While testosterone does play into a woman’s libido, estrogen provides an overwhelming influence.10]Lorraine Dennerstein, John Randolph, John Taffe, Emma Dudley, Henry Burger. Hormones, Mood, Sexuality, and the Menopausal Transition, Fertil Steril. 2002

Many studies show that a woman’s interest in sex has a lot to do with her menstrual cycle timing and typically peaks midcycle around the time of ovulation.11S H Van Goozen, V M Wiegant, E Endert, F A Helmond, N E Van de Poll. Psychoendocrinological Assessment of the Menstrual Cycle: The Relationship Between Hormones, Sexuality, and Mood, Mood, Arch Sex Behav.1997

Cortisol and stress-hormone production also plays an important role in sex drive.  These glucocorticoids can disrupt the production of estrogen, which can sabotage libido.12Fatma Ela Keskin, Hande Mefkure Özkaya, Mazhar Ortaç, Emre Salabaş, Ateş Kadıoğlu, and Pınar Kadıoğlu. Sexual function in women with Cushing’s Syndrome: A controlled study, Turk J Urol. 2018

This makes sense since the body prioritizes survival with a stress response over reproduction.

For a woman to truly optimize her sex drive, she must optimize estrogen production, which requires lowering glucocorticoid response.

This is best done by lowering stress and managing the HPA Axis.

Understanding The Natural Male Libido


Testosterone levels play a large role in maintaining a healthy sex drive for menThe male libido is, of course, a complicated system, but one of the primary issues is testosterone.

Testosterone is a hormone that regulates sex drive, desire, and sperm production.

It also plays a significant role in other important health aspects like muscle growth, sleep, and mood.

Like estrogen, testosterone production is highly dependent on the HPA axis function and keeping the body’s stress response low.13George N. Nassar; Fernando Raudales; Stephen W. Leslie.. Physiology, Testosterone, StatPearls. 2020

High stress-hormone production due to physical and emotional stress can sap the body of its ability to produce testosterone.

Low testosterone can be one source of sexual issues. Fortunately, some nootropic remedies may give you the boost you need.

  • 7 All-Natural Forms of Magnesium
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Sex Hormones and Gut Health

New research into the microbiome is revealing a connection between gut bacterial diversity and sex hormones.14Ji-Hee Shin , Young-Hee Park, Minju Sim, Seong-Ah Kim, Hyojee Joung, Dong-Mi Shin. Serum level of sex steroid hormone is associated with diversity and profiles of human gut microbiome, Res Microbiol. Jun-Aug 2019

Having a gut filled with diverse species of bacteria is proving to be beneficial for overall health and has been shown to influence both testosterone in men and estrogen in women positively.

A good way to get a diverse microbiome is to eat a diverse diet made up of whole-foods.  This includes organic fruits, vegetables, meat from pasture-raised animals, and minimal fried foods.

Probiotics are also a great way to add diversity to your microbiome.

The point of a good probiotic is to supply your gut with bacterial strains that you can’t get from food.  This includes fermented foods.

Most people are lacking many beneficial bacterial strains due to a history of antibiotics, pharmaceuticals, and poor diet.

A good probiotic will reseed your gut with good bacteria, which can help boost sex hormone production.  Check out my recommendation below.





Best Nootropic Supplements for Sex Drive and Libido

1. Blood Sugar Breakthrough

Blood Sugar Breakthrough

Stabilizes and promotes healthy blood sugar levels

Uncontrolled blood glucose levels has been identified as one of the major causes of erectile dysfunction, impotence and lowered sex drive among men.

This is especially true among diabetics and prediabetics15Giovanni Corona , Giulia Rastrelli, Valdo Ricca, Emmanuele A Jannini, Linda Vignozzi, Matteo Monami, Alessandra Sforza, Gianni Forti, Edoardo Mannucci, Mario Maggi, Risk factors associated with primary and secondary reduced libido in male patients with sexual dysfunction, J Sex Med. 2013

Excessively high blood sugar levels negatively alter several body systems such as the circulatory, nervous, and the endocrine system which in turn affects the sexual drive of an individual. 16Kelli L. Copeland, BA, Jeanette S. Brown, MD, Jennifer M. Creasman, MSPH, Stephen K. Van Den Eeden, PhD, Leslee L. Subak, MD, David H. Thom, MD, PhD, Assiamira Ferrara, MD, PhD,and Alison J. Huang, MD, MAS, Diabetes Mellitus and Sexual Function in Middle-Aged and Older Women, Obstet Gynecol. 201317Author(s), Sexual dysfunctions in patients with diabetes: a study from Iran, Reprod Biol Endocrinol. 2010

Blood Sugar Breakthrough effectively treats this metabolism-libido pathway as it's formula is designed to optimize blood glucose levels and overall metabolism, which will ultimately boost your sex drive and sexual performance.

2. Magnesium Breakthrough

Magnesium for Studying

#1 Magnesium Product

Magnesium is crucial in production of various vital hormones. Researchers have observed and linked this mineral with muscle growth, sex drive, testosterone level and production of gametes i.e., sperms in males and eggs in females.18ViskiJ. SzöllosiA. S. KissA. Csikkel-Szolnoki, Effects of Magnesium on Spermiogenesis, Kluwer Academic Publishers. 1997 Hence, it has been proven to maximize sex drive and libido.19Vedat Cinar, Yahya Polat, Abdulkerim Kasim Baltaci & Rasim Mogulkoc , Effects of Magnesium Supplementation on Testosterone Levels of Athletes and Sedentary Subjects at Rest and after Exhaustion, Biological Trace Element Research. 2010

Literature suggests that uptake of dietary magnesium regularizes the levels of DHEA (dehydroepiandrosterone), boosts testosterone levels, ameliorate symptoms of premature ejaculation and erectile dysfunction, enhance libido, and also aids with conception and fertility.20David A. Kalmbach PhD, J. Todd Arnedt PhD Vivek Pillai PhD Jeffrey A. Ciesla PhDThe Impact of Sleep on Female Sexual Response and Behavior: A Pilot Study, Wiley Online Library. 201921Rachel Leproult, PhD; Eve Van Cauter, PhD, Effect of 1 Week of Sleep Restriction on Testosterone Levels in Young Healthy Men, JAMA. 2011

One of the main components of Magnesium Breakthrough is magnesium citrate. This form of magnesium is particularly recommended for overall reproductive health and wellness in both men and women.

3. Testo Lab Pro

Testo Lab Pro Best Nootropics for Sex Drive and Libido

Natural Testosterone-Boosting Blend

TestoLab Pro is a top choice for naturally boosting testosterone and overall masculine energy. 

This stack boosts sexual vitality and desire while enhancing strength, muscle pump, motivation, and mental clarity.

TestoLab's formula includes compounds that boost your brain's natural testosterone messaging system like the bio-active form of Ashwagandha (KSM-66), D-Aspartic Acid, and Mucuna Pruriens Extract.

The included Luteolin is a natural testosterone preservation system that keeps your manufactured T from being hijacked and converted into estrogen. 

The added Zinc, Magnesium, and Vitamin D help keep your hormone production pathways optimized for proper nutrient synthesis while at the same time reducing stress hormones.

4. Reishi

A staple in Eastern medicine

Reishi mushroom is well known for its aphrodisiac properties. This mushroom has been used broadly to promote sex drive since medieval period.22Hammad Ahmed & Muhammad Aslam, Evaluation of aphrodisiac activity of ethanol extract of Ganoderma lucidum in male Wistar rats, Clinical Phytoscience. 2018

Reishi's anti-inflammatory properties along with immune boosting ability help keep you on your game while reducing stress levels.23Nerida L. Klupp, Hosen Kiat, Alan Bensoussan, Genevieve Z. Steiner, and Dennis H. Chang, A double-blind, randomised, placebo-controlled trial of Ganoderma lucidum for the treatment of cardiovascular risk factors of metabolic syndrome, Sci Rep. 2016

 These physical benefits translate into the bedroom with boosted performance and desire.

Reishi also has adaptogenic properties that have been shown to increase fertility in both men and women.24Ding-Tao Wu, Yong Deng, Ling-Xiao Chen, Jing Zhao, Anton Bzhelyansky,and Shao-Ping Li, Evaluation on quality consistency of Ganoderma lucidum dietary supplements collected in the United States, Sci Rep. 2017

Freshcap Mushrooms provide the highest percentage of beta glucans and fruiting body nutrients, making this mushroom product my preferred choice for Reishi.

5. Mind Lab Pro

Mind Lab Pro Best Nootropic for Sex Drive and Libido

#1 Nootropic For Beginners

  • Mind Lab Pro's 11 nootropic ingredients work synergistically to enhance sex drive and performance. 
  • This formula includes adaptogens and amino acids that lower your body's stress response, boosting sex hormone production.
  • You also get potent nootropics and amino acids that keep your mood right and your brain thinking sexy thoughts.
  • The included B-vitamin co-factors help optimize absorbability.
  • The supplements themselves are 3rd party tested and free of excess fillers and toxic ingredients. 
  • I love this stack for nootropic newbies and experienced nootropic users alike.

6. Qualia Mind

Qualia Mind For Sex Drive And Libido

Most Nootropics Per Serving

  • Qualia Mind's advanced formula includes 28 high-quality ingredients that work synergistically to give you a powerful boost in the sex drive.
  • The amino acids and cholinergic nootropics combine to boost sexual desire, motivation, physical responsiveness, and energy.
  • Adaptogens and B-vitamins work to lower stress, which will increase sex hormone production.
  • Caffeinated and non-caffeinated versions are available

7. Cordyceps

Cordyceps is a medicinal mushroom, which has been used therapeutically on the Asian continent for centuries.

Consuming cordyceps just a few times a week has been shown to enhance vigor and vitality which ultimately leads to better sex drive and libido.25Kanitta Jiraungkoorskul and Wannee Jiraungkoorskul, Review of Naturopathy of Medical Mushroom, Ophiocordyceps Sinensis, in Sexual Dysfunction, Pharmacogn Rev. 2016

It offers an organic and natural substitute to other pharmaceutical drugs used to enhance libido.26Jin Xu, Ying Huang, Xiang-Xiang Chen, Shuai-Chao Zheng, Peng Chen, Ming-He Mo, The Mechanisms of Pharmacological Activities of Ophiocordyceps sinensis Fungi, Phytother Res. 2016

This mushroom has been found to promote sperm production, enhance stamina, improve erectile function, cure male impotence, and upsurge sexual desire in both men and women.27Kanitta Jiraungkoorskul , Wannee Jiraungkoorskul, Review of Naturopathy of Medical Mushroom, Ophiocordyceps Sinensis, in Sexual Dysfunction, Pharmacogn Rev. 2016

Freshcap Mushrooms provide the highest percentage of beta glucans and fruiting body nutrients, making this mushroom product my preferred choice for Cordyceps.

8. Pine Bark Extract

Pine Bark Extract for Sex Drive And Libido

All natural ADHD remedy

Pine Bark Extract is another natural remedy for erectile dysfunction.

This extract of the Pinus pinaster tree can increase nitrous levels in the blood. This natural chemical compound improves overall vascular health, but can specifically enhance erections.

Another benefit of pine bark is that it can improve sperm count and mobility.

But the effects of pine bark extract on libido is not limited to men. One study found that pine bark extract “improves sexual function across all domains” in healthy women. 28Bottari, Belcarlo. Lady Prelox® improves sexual function in generally healthy women of reproductive age., Minerva Ginecol 2013

Because blood flow is so vital for desire and sexual performance, pine bark extract can be a great way to support your sex drive holistically.

9. Mucuna Pruriens

Ashwagandha for Sex Drive And Libido

Natural dopamine

Mucuna Pruriens is an amazing nootropic for both male sexual function and desire.

It is a natural testosterone booster, which means better sexual performance, but also increased motivation.

Mucuna Pruriens is also a great source of L-dopa which adds to its ability to boost libido.

Clinical studies show Mucuna's potency for also boosting overall male fertility.

Read more about Mucuna Pruriens

10. Ashwagandha

Ashwagandha for Sex Drive And Libido

Traditional herb with potent relaxing effects

Ashwagandha is a nootropic herb that Southeast Asian cultures have been using for millennia to treat many issues, including low libido. Its name literally means “smell of horse” in Sanskrit (and we all know what else horses are famous for)

Ashwagandha has been proven to raise testosterone in males.

It can also increase the amount of oxygen circulating in the body, resulting in better erections. These two benefits could translate to better performance in bed.29Wankhede, Langade, Joshi, Sinha, Battacharyya. Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial., Journal of the International Society of Sports Nutrition. 201530Lopresti, Drummond, Smith. A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha (Withania somnifera) in Aging, Overweight Males, American Journal of Men's Health. 2019

This herb is considered an adaptogen, meaning that it can keep stress levels in check.

Trials show that it substantially lowers the stress hormone cortisol, which is the enemy of testosterone.

We all know how difficult it is to get in the mood when you’re feeling anxious, and ashwagandha could potentially alleviate some of that pressure.31Chandrasekhar. A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults, Indian Journal Of Psychological Medicine 2014

Ashwagandha can also increase the quality of sperm, which may be helpful if you are trying to conceive.32Mahdi, Shukla. Withania somnifera Improves Semen Quality in Stress-Related Male Fertility., Evidence-Based Complementary And Alternative Medicine 2009

And this nootropic is not only beneficial to men; it can also improve the sex life of women as well. One study found that it was effective in treating women who were suffering from a lack of arousal or difficulty achieving orgasm.33Dongre, Langade. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study, Biomed Res Intl 2015

All in all, ashwagandha is one of the best natural remedies for low sex drive out there.

11. Alpha-GPC

Alpha GPC for Sex Drive and Libido

Great source of choline that works well in nootropic stacks

Boosting your acetylcholine levels can also improve your sex life. Acetylcholine (ACh) is the most abundant neurotransmitter in your nervous system, and it affects pretty much every system in the body, including libido and sex drive.

ACh is necessary to send impulses from your brain to your nether regions. 34Choline: Why You Should Eat Your Egg Yolks And Take Krill, 2016

It can also boost levels of nitrous oxide in your blood, another huge factor in sexual performance, especially for men.35Carriere, El-Fakahany. Choline is a full agonist in inducing activation of neuronal nitric oxide synthase via the muscarinic M1 receptor, Pharmacology. 2000

12. Citicoline

Citicoline for Sex Drive and Libido

Supercharged source of choline for your brain

By increasing your intake of choline, you can help your body produce more ACh and allow you to step your game up in the bedroom.

Alpha GPC and Citicoline are both potent sources of choline that some people have had success in improving their sex lives.

Choline is a great holistic way to get your nervous system more in tune, which can have wide-ranging benefits.

Wrapping Up

While these are the most widely used supplements for libido, this field is ever-expanding (pun intended).

What Nootropics are you using for boosting your sex drive? Lets us know in the comments. (I know we’re all adults here, but please try to keep it clean!)

About the author:

Erik Levi, FNTP

Erik Levi is a co-founder of and a certified holistic nutritional therapy practitioner.

As an NTP Erik takes a nutrition first approach to health. He has worked with many different people to help them use nutrition to optimize their quality of life.

Erik believes that mental health is a physiological process and cognitive enhancement is not something that can be achieved by just taking some pills with good Amazon reviews.

Instead, true cognitive enhancement comes with the right balance of nutrients, movement, and gratitude. Erik continues to stay up to date with the most current nootropic and holistic health research and promises to deliver the best solutions possible.

You can check out his personal health blog/podcast/YouTube Channel all under the name Holistic A-Hole.

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