7 Best Nootropics For Addiction Recovery

Key Takeaways:

Some nootropics may help ease the pain of quitting addictive substances

Depending on the substance, nootropics may be useful for controlling cravings

Some nootropics could counteract the negative mental effects of withdrawal

Nootropics are over-the-counter and do not require a physician to take

You should consult your doctor before using nootropics as part of your recovery plan

7 Best Nootropics For Addiction Recovery

Overcoming addiction and dealing with withdrawals is never easy.

The most critical factors in getting and staying clean are always going to be the same: A good support network, getting the professional help you need, and time to heal.

It’s also essential to take care of your body holistically, with proper nutrition, exercise (if you are able), hydration, and sleep.

These processes will help your brain and body eventually reset to their natural baseline.

However, there may be some over-the-counter nootropic substances that may help ease the pain and support a healthy transition into sobriety.

What Are The Best Nootropics for Addiction Recovery – Quick Answers

Blood Sugar Breakthrough #1

Blood Sugar Breakthrough

Stabilizes and promotes healthy blood sugar levels
Mind Lab Pro #2

Mind Lab Pro

Science-backed nutrition for your brain
Check PriceBuy 3 bottles, get 1 free with our links
Reishi #3


A staple of Eastern medicine
Magnesium Breakthrough #4

Magnesium Breakthrough

#1 Magnesium Product
Qualia Mind #5

Qualia Mind

Most Nootropics Per Serving
L-Theanine #6


The all-natural "chill pill"
Aniracetam #7


Popular nootropoic for boosting focus and mood
Citicoline #8


Get more done in your day
Adrafinil #9


An over-the-counter version of Modafinil
NALT (L-Tyrosine) #10

NALT (L-Tyrosine)

The natural way to boost serotonin

Best Nootropics For Withdrawal

Nootropics were initially developed as neuroprotectants, so it would make sense that they might have been used for addiction recovery.

These supplements come in many different forms.  Some of them might be able to heal the brain after abusing it through other chemicals.

They might clear out oxidative damage or help the regrow neurons.

Others might be useful for softening the cravings and lowering the chance of relapse.

5 Best Nootropics For Addiction Recovery

Stabilizes and promotes healthy blood sugar levels

Blood Sugar Breakthrough

  • Provides the body with essential energy

  • Helps regulate mood swings because it improves cognitive abilities

  • It assists in addiction recovery by preventing metabolic syndrome and diabetes development

  • Decreases sugar cravings

If you’re looking for a natural way to regulate your blood sugar and improve your ADHD symptoms, Blood Sugar Breakthrough may be worth trying!

Blood Sugar Breakthrough is a potent Adderall replacement as it helps stabilize your body and brain’s glucose metabolism.

Researchers have found a correlation between ADHD and blood sugar which makes sense since the ADHD brain craves dopamine stimulation that can be obtained through simple carbs and high-sugar foods. You’ve most likely experienced moments of hunger where you found it impossible to focus.1Mark F McCarty, James J DiNicolantonio , Neuroprotective potential of high-dose biotin, Med Hypotheses. 2017

Unstable blood glucose levels enhance this craving and deprive your brain of the dopamine it needs. Blood Sugar Breakthrough optimizes your body’s glycemic response to food which helps stabilize your blood sugar and focus.2NIH, Chromium, NIH. 20213Kate Petersen Shay, Régis F. Moreau,1 Eric J. Smith, Anthony R. Smith, and Tory M. Hagen, Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential, Biochim Biophys Acta. 2009

This formula also has some natural, cognition-stimulating ingredients, such as biotin, chromium, and alpha-lipoic acid, which can boost overall cognition.

Dysregulated blood sugar levels have been associated with an increased risk of cognitive decline, development of depressive symptoms, and formation of addictive behavior patterns.4Lynette C. Daws, Malcolm J. Avison, Sabrina D. Robertson, Kevin D. Niswender, Aurelio Galli, and Christine Saunders, Insulin signaling and addiction, Neuropharmacology. 2012

Studies also suggest that people who have had a history of substance abuse are at an increased risk of development of metabolic syndrome and diabetes due to increased cell damage and the adverse effects of opioids on glucose homeostasis.5Omorogieva Ojo, Xiao-Hua Wang , Osarhumwese Osaretin Ojo , Jude Ibe, The Effects of Substance Abuse on Blood Glucose Parameters in Patients with Diabetes: A Systematic Review and Meta-Analysis, Int J Environ Res Public Health. 20186C Taha, A Klip, The insulin signaling pathway, J Membr Biol. 1999

Blood Sugar Breakthrough can help to bring the blood glucose levels back into balance and thus assist the process of addiction recovery.


  • Contains natural ingredients that have been clinically proven to help lower blood sugar levels
  • Has been shown to help people lose weight
  • comes with a money-back guarantee, so you can feel confident that you’re not wasting your money if it doesn’t work for you


  • Can be a bit pricey

Science-backed nutrition for your brain

Mind Lab Pro

Mind Lab Pro
Check PriceBuy 3 bottles, get 1 free with our links
Check PriceBuy 3 bottles, get 1 free with our links
  • Address addiction in a holistic manner

  • Improve your willpower to stay on track with good habits

  • Enhance mood and feel-good factors through complex neurotransmitter systems

  • All ingredients are 3rd party tested, free of toxic ingredients

Mind Lab Pro is my top nootropic choice for overcoming addiction.

This stack includes 11 high potency ingredients that build neurotransmitters, which helps with willpower and feeling good.

The adaptogenic herbs add support by reducing brain inflammation and stress hormones. 

There’s also B-vitamins and phosphatidylserine for added support. 

The supplements themselves are 3rd party tested and free of excess fillers and toxic ingredients. 

I love this stack for nootropic newbies and experienced nootropic users alike.


  • Proven to boost overall cognitive performance including memory, focus, mood, creativity, motivation, and overall well-being.
  • Potent blend of all-natural nootropics, herbs, amino acids, vitamins, and minerals.
  • Good for Experienced Biohackers and those new to nootropics.
  • Caffeine Free
  • No artificial fillers or toxic preservatives
  • Affordable Price


  • Ingredients are lower dosed.
  • Fewer ingredients than other leading nootropic stacks

A staple of Eastern medicine


  • Promotes long-term focus and mental energy

  • Stimulate neurogenesis

  • Boosts immune system

  • Calm effects on central nervous system

Reishi mushroom is a medicinal mushroom that helps both addiction recovery and mitigate harsh withdrawal symptoms.7Huihui Wu, Shanshan Tang , Zhaoqin Huang, Qian Zhou , Ping Zhang , Zuohong Chen, Hepatoprotective Effects and Mechanisms of Action of Triterpenoids from Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) on α-Amanitin-Induced Liver Injury in Mice, Int J Med Mushrooms. 2016

It has immunomodulating effects that keep your body’s defense mechanisms calm, balances hormones, and promotes hepatic health, which are all crucial for successful addiction recovery.8Huihui Wu, Shanshan Tang, Zhaoqin Huang, Qian Zhou, Ping Zhang , Zuohong Chen, Hepatoprotective Effects and Mechanisms of Action of Triterpenoids from Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) on α-Amanitin-Induced Liver Injury in Mice, Int J Med Mushrooms. 2016;

This mushroom contains many essential macro- and micro- nutrients, which will help you from feeling tired, dizzy, and lethargic during the recovery period.

Reishi also promotes neuroplasticity, and enhances antioxidant status in the body to keep you feeling sharp and healthy while abstaining from substances..9Sissi Wachtel-Galor, John Yuen, John A. Buswell, and Iris F. F. Benzie., Chapter 9Ganoderma lucidum (Lingzhi or Reishi), CRC Press/Taylor & Francis. 2011

Freshcap Mushrooms provide the highest percentage of beta glucans and fruiting body nutrients, making this mushroom product my preferred choice for Reishi.


  • May help improve sleep quality and reduce stress levels
  • Can be consumed in many different forms, such as capsules, powders, teas, and tinctures
  • Used in Asia for centuries as a medicinal mushroom


  • Common side effects include gastrointestinal upset and nausea
  • Not recommended for people with autoimmune disease or taking immunosuppressive medication

#1 Magnesium Product

Magnesium Breakthrough

  • Reduce the likelihood of addiction

  • Promote improved health in general

  • Reduces symptoms of withdrawal

  • Lessen severity and duration of addiction

Research suggests that the intake of Magnesium in supplemental form may assist in the reduction of the intensity of addiction to alcohol, cocaine, opiates, amphetamine, and nicotine.10Mihai Nechifor, Magnesium in drug abuse and addiction, University of Adelaide Press. 2011

The underlying mechanism for magnesium’s potential role in addiction recovery may be attributed to the fact that drug abusers and alcohol consumers often have relatively lower levels of magnesium concentration intracellularly and also in their blood plasma when compared to non-drug dependent individuals.11Mihai Nechifor, Magnesium in addiction – a general view, Magnes Res. 201812Kari Poikolainen & Hannu Alho , Magnesium treatment in alcoholics: A randomized clinical trial, Substance Abuse Treatment, Prevention, and Policy volume 3. 2008

Not only does magnesium help in emerging from addiction and dependency, it may also help in reducing the intensity of withdrawal symptoms and managing stress in drug-dependent individuals.13Mihai Nechifor, Magnesium in addiction – a general view, Magnes Res. 2018

Magnesium Breakthrough contains is a good amalgamation of various absorbable forms of dietary magnesium. Hence, it is highly recommended as a useful supplement in addiction recovery.

Most Nootropics Per Serving

Qualia Mind

  • Help with recovery and withdrawal

  • Boost dopamine levels

  • Improve mental clarity and concentration

  • Stimulates the mind to be more productive

Qualia Mind’s comprehensive formula contains several amino acids and nootropics that work synergistically to calm the mind while boosting dopamine and motivation, which is essential when dealing with recovery and withdrawal.

You also get several adaptogens and B-vitamins to alleviate the stress response and keep you cool in tough times.

Vitamins B6, C, and D3 improve the conversion of Dopamine to Norepinephrine, which is vital to help your brain appropriately utilize these neurotransmitters.

Caffeinated and non-caffeinated versions are available.


  • Most advanced nootropic formula on the market
  • All-natural ingredients
  • Clean formula: No toxic fillers or necessary preservatives
  • Many positive user testimonials
  • Option for less potent Qualia Focus Available
  • Over 50% off 1st Bottle
  • Use “15INSAVINGS” For Additional 15% Off


  • Large dose of 7 pills
  • More expensive than most other nootropics
  • More ingredients not always better.

The all-natural “chill pill”


  • Help to retain sobriety and reduce withdrawal symptoms

  • Research has shown that it can lower anxiety and increase mood

  • Effective at calming the body during periods of high stress

  • Benefits for everyone who wants to stay calm

L-theanine is an amino acid found in tea leaves, and it’s the compound that’s responsible for tea’s relaxing effects.

This might be valuable for recovering addicts, who may appreciate l-theanine’s non-habit forming chill-out effects. According to research, it can lower anxiety through its action on the GABA, dopamine, and serotonin system.

This process could help calm you down during the stressful period while you are detoxing. L-theanine helped addicted primates stay clean from opiates during one trial.14Laura E. Wise, et al. L-theanine attenuates abstinence signs in morphine-dependent rhesus monkeys and elicits anxiolytic-like activity in mice, Pharmacol Biochem Behav. 2012

Quitting any substance is always going to be tough and stressful. Withdrawing can trigger your body’s fight-or-flight response, which can cause a lot of anxiety and may cause a relapse.

Luckily, l-theanine may reduce these symptoms and help you stay calm as you detox.

Learn More about L-theanine

Popular nootropoic for boosting focus and mood


  • Boosts creativity and productivity

  • Exhibits both stimulant-like effects and calming, anti-anxiety properties

  • Helps with mood changes associated with withdrawal

  • Provides a subtle mood boost without the risk of addiction

Aniracetam is a nootropic in the racetam family and is known for its powerful stimulating and cognition-enhancing effects.

Although there has yet to be clinical research, there is some anecdotal evidence that it can help with addiction recovery.

Aniracetam has a subtle effect on mood, through its action on the acetylcholine, dopamine, and serotonin systems.

It can increase feelings of wellbeing and decrease anxiety somewhat, which could potentially offset some of the depressive symptoms of withdrawals and recovery.

Although it can make you feel good, it is not known to be addictive itself, which is a positive.

Learn More about Aniracetam

Get more done in your day


  • Promotes improved mental health

  • Stimulates the production of dopamine

  • Reduces risk for addiction relapse

  • Increases brain functionality

Citicoline is an excellent source of choline, a nutrient that could be valuable in fighting addiction.

It is also a precursor of dopamine, which could have therapeutic use. Researchers are taking note.

Although there are not many current studies, one meta-analysis saw that citicoline had promising results treating a variety of addictions.

They concluded that citicoline had “promise for alcohol and cannabis dependence and in reducing food consumption.”15Wignall ND, Brown ES. Citicoline in addictive disorders: a review of the literature, Am J Drug Alcohol Abuse. 2014

Citicoline also has a minimal side-effect profile and is extremely safe. We highly recommend it for any detox stack.

Learn More about Citicoline


  • Great choice for students or anyone looking to boost their cognitive performance
  • Improves focus, attention, and impulse control in people with ADHD
  • Generally well tolerated and side effects are rare.
  • All-natural supplement
  • Easily found online or in health food stores


  • May cause stomach upset, headache, dizziness, and insomnia

An over-the-counter version of Modafinil


  • Proven to be effective in boosting energy and mental clarity

  • Safe for use on a daily basis or when coming off of harder stimulants like cocaine

  • Low potential for addiction, making it safer than other substances

Adrafinil is essentially an over the counter version of modafinil, the prescription smart drug.

It is a mild stimulant that can increase arousal, wakefulness, and cognition, although it is not nearly as intense as other stimulants like amphetamine or cocaine.

It has a low potential for addiction and may be useful for helping treat other addictions. Because it is a mild stimulant, it could be a possible replacement for other, more dangerous substances.

Similar to the way suboxone can treat heroin abuse, it could keep cravings under control and help keep people sober for longer periods. There is some initial clinical evidence that this is the case.16Ann L.Anderson, et al. Modafinil for the treatment of cocaine dependence, Drug and Alcohol Dependence 2009

Withdrawals are also associated with brain fog and cognitive problems.

Adrafinil could help cut through the mental fatigue and allow people in recovery to be more motivated and productive as they go about life during their withdrawals.

However, be aware that there is a small chance that adrafinil could become addictive. We would recommend checking in with a physician or counselor before trying adrafinil as part of your detox regimen.

This effect is highly unusual, but there are some case studies.17Raman Krishnan, Krishnan Vengadaragava Chary. A rare case modafinil dependence, J Pharmacol Pharmacother. 2015

Learn More about Adrafinil


  • Adrafinil has been shown to improve working memory, executive function, and vigilance in healthy adults.
  • In one study, adrafinil was found to be as effective as methylphenidate (Ritalin) at reducing ADHD symptoms.
  • May also help to improve cognitive function in people with Alzheimer’s disease and other forms of dementia.
  • Can help you stay awake longer


  • Most common side effects reported are headache, nausea, and anxiety.
  • Adrafinil is a schedule IV controlled substance in Canada and is classified as a prescription drug.
  • not currently approved by the FDA

The natural way to boost serotonin

NALT (L-Tyrosine)

  • Help maintain balance of mood and motivation

  • Prevent cravings for drugs to release dopamine

  • Cure the low dopamine withdrawal symptoms

  • Decrease likelihood to relapse

L-tyrosine is a common amino acid found in foods like cheese. It is an essential building block of neurotransmitters like dopamine and norepinephrine, which are critical for regulating mood and motivation.

People struggling with addiction often have imbalances in these transmitters. Many drugs use up dopamine stores and downregulate dopamine receptors.

So, when you stop using them, you suffer from the effects of low dopamine.

Symptoms include depression, anxiety, and intense cravings for the dopamine release the drugs provide.

Theoretically, taking an l-tyrosine supplement could boost levels of dopamine naturally and help curb some of the withdrawal symptoms.

L-tyrosine may also improve focus, reduce stress, and support healthy brain chemistry during the stress of withdrawals.

If you want to go this route, we recommend taking NALT, which is a more bioavailable form of l-tyrosine.

Although there is currently no clinical evidence to support this use, many people have reported success kicking opiates by using l-tyrosine.

Learn More about NALT


  • Non-addictive and has few side effects
  • Does not interact with other medications, so it can be taken safely by people who are taking other medications for other conditions
  • Relatively inexpensive and is covered by many insurance plans


  • Can cause withdrawal symptoms in people who stop taking it suddenly
  • Can also cause liver damage, so people with liver problems should not take nalt

Wrapping Up

Substance use disorders occur when the recurrent use of alcohol and/or drugs causes clinically significant impairment, including health problems, disability, and failure to meet major responsibilities at work, school, or home.

We highly recommend you explore substance abuse counseling along with any supplement regimen.

If you need help immediately, we recommend reaching out via Substance Abuse and Mental Health Services National Helpline.

Do you have a recovery story or strategy to share? Tell us about it in the comments!

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Erik Abramowitz is a certified Nutritional Therapy Practitioner (NTP), Naturopathic Doctoral student, health coach, and father. He is the primary content creator for HolisticNootropics.com and the host of the Holistic Nootropics Podcast.

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