How MAO Inhibitors Fight Depression

What Are MAO Inhibitors? Monoamine oxidase inhibitors (MAOIs) are a class of drugs that prevent the breakdown of monoamines, including vital neurotransmitters such as dopamine and serotonin. MAOs oxidize and remove these transmitters from the synaptic cleft. By preventing this action, MAOIs can indirectly raise levels of certain chemicals in the brain. This could potentially …

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How glutamate excitotoxicity effects brain function

Glutamate Excitotoxicity – A Powerful Neurotransmitter

Glutamate excitotoxicity is a significant factor in cognitive dysfunction that you may not be aware of, but really should be. It can play a role in any number of issues, including: Attention problems Anxiety Brain fog Low mood Depression Cognitive decline Neuron damage In fact, glutamate excitotoxicity seems to pop up as a factor in …

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COMT gene mutations

The Ultimate COMT Gene Guide | Mood, Mutations, & More

What Does The COMT Gene Do? One of the most important single genes when it comes to cognitive function and mental performance is the COMT gene. The COMT gene encodes for the catechol-O-methyltransferase (COMT) enzyme. This enzyme is critical for brain function, as it is responsible for degrading catecholamines. Catecholamines are the class of neurotransmitters …

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Is Neurofuel (Ciltep) A Good Nootropic – Benefits, Comparisons, & User Reviews

Neurofuel, formerly Ciltep, is a family of preformulated nootropic stacks for everything from memory and focuses enhancement to mood stabilization. Natural Stacks, the makers of Neurofuel, promise “increased motivation, improved concentration, mood, and enhanced ability to study.” Neurofuel is one of the first commercially available nootropic stacks on the market, debuting in 2012. It has …

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Sarcosine: Benefits, Dosing, Where To Buy, And More!

Sarcosine – An Overview Sarcosine (N-methylglycine) is a precursor and derivative of the amino acid glycine. Physicians primarily prescribe sarcosine for treating schizophrenia, although it may also have some nootropic benefits for: Depression OCD Memory Neuroprotection Sarcosine works by activating the NMDA (N-methyl-D-aspartate) receptor. Researchers believe that it achieves most of its therapeutic effects through …

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Phenylpiracetam: Benefits, Dosing, Where To Buy, And More!

Phenylpiracetam – An Overview Phenylpiracetam (AKA phenotropil or phenotropyl) is a phenyl derivative of piracetam. Piracetam was the original racetam nootropic, and phenylpiracetam is a newer version that acts quicker and has higher bioavailability. It is more potent and has a broader range of use. Nootropics users take phenylpiracetam for: Focus Improved Cognition Memory and …

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