What Are The Best Nootropics for Sleep - Quick Answers
|Magnesium||#1 Magnesium Product||Learn More|
|Red Light Sauna||Heal while you sleep||Learn More|
|Qualia Night||#1 Nootropic Stack for Sleep||Learn More|
|CBD||Non-Psychoactive Cannabis||Learn More|
|Performance Lab Sleep||Ultramodern sleep aid helps you wake in the morning ready to perform||Learn More|
|Circadian Rhythm Blend||Promotes a healthy circadian rhythm so that you can sleep deeper.||Learn More|
|Delta 8 THC||Regulates sleep cycle and helps you experience calm, promotes rest||Learn More|
|Mind Lab Pro||#1 Nootropic For Beginners||Learn More|
|L-ornithine||Holistic stamina and stress support||Learn More|
Benefits of Nootropics and Supplements For Sleep
Nootropics and supplements have a wide spectrum of health benefits, especially with regard to sleep.1Sheldon Cohen, William J Doyle, Cuneyt M Alper, Denise Janicki-Deverts, Ronald B Turner, Sleep habits and susceptibility to the common cold, Arch Intern Med. 2009
Nootropics are natural and safe alternatives to many contemporary medications and come with minimal side effects.
Most nootropics are non-habit forming in nature, which is a great advantage when compared to many other similar medications or drugs. As an added benefit, nootropics support brain health and help to regulate the circadian rhythm.
Common Sleep Problem Statistics
The statistics regarding sleep patterns and sleep associated disorders are quite concerning.
For instance, about 35.2% of the adult population in the United States of America are sleep deprived as they tend to sleep for less than seven hours per night on average.2National Center for Chronic Disease Prevention and Health Promotion, Division of Population Health, Sleep and Sleep Disorders, National Center for Chronic Disease Prevention and Health Promotion, Division of Population Health. 20173Nathaniel F. Watson, MD, MSc, Moderator, M. Safwan Badr, MD, Gregory Belenky, MD, Donald L. Bliwise, PhD, Orfeu M. Buxton, PhD, Daniel Buysse, MD, David F. Dinges, PhD, James Gangwisch, PhD, Michael A. Grandner, PhD, MSTR, CBSM, Clete Kushida, MD, PhD, Raman K. Malhotra, MD, Jennifer L. Martin, PhD,Sanjay R. Patel, MD, MSc, Stuart F. Quan, MD, and Esra Tasali, MD, Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society on the Recommended Amount of Sleep for a Healthy Adult: Methodology and Discussion, J Clin Sleep Med. 2015
In the U.S., it is estimated that approximately 135,000 to 200,000 people have narcolepsy, which is a chronic sleep disorder characterized by extreme daytime drowsiness.5K Nishiyama , J V Johnson, Karoshi–death from overwork: occupational health consequences of Japanese production management, Int J Health Serv. 1997
Sleep for Optimal Mental, and Physiological Function
Sleep is a vital physiological function that is essential in maintaining the homeostasis of our body. Adequate sleep is crucial for the maintenance of optimal cognitive and behavioral functions.7NINDS, Brain Basics: Understanding Sleep, NINDS . 20198U.S. National Library of Medicine, Sleep and your health, U.S. National Library of Medicine. 2021
Melatonin and Circadian Rhythm
Melatonin acts as a time cue for our circadian rhythm. In other words, melatonin is similar to an internal clock that drives our sleep-wake cycle.9C Cajochen, K Kräuchi, A Wirz-Justice, Role of melatonin in the regulation of human circadian rhythms and sleep, J Neuroendocrinol. 2003
The melatonin hormone is secreted by the pineal gland in response to darkness or absence of light, which helps to synchronize our circadian rhythm between sleep-wake times.10Sylvie Tordjman, Sylvie Chokron,2 Richard Delorme, Annaëlle Charrier, Eric Bellissant, Nemat Jaafari, and Claire Fougerou, Melatonin: Pharmacology, Functions and Therapeutic Benefits, Curr Neuropharmacol. 2017
Neurotransmitters and Sleep
Enhanced serotonin activity has been linked to sleep deprivation. Serotonin is a neurotransmitter of particular interest to sleep researchers because it can induce both wakefulness or sleep depending on the part of the brain and the corresponding receptor which is involved in the response. 11Christopher J. Watson, Ph.D., Helen A. Baghdoyan, Ph.D., and Ralph Lydic, Ph.D, Neuropharmacology of Sleep and Wakefulness, Sleep Med Clin. 201112Reidun Ursin, Serotonin and sleep, Sleep Med Rev. 2002
Norepinephrine is a wake-promoting neurotransmitter, that is, an increase in Norepinephrine promotes wakefulness and reduces sleep.14Christopher J. Watson, Ph.D., Helen A. Baghdoyan, Ph.D., and Ralph Lydic, Ph.D., Neuropharmacology of Sleep and Wakefulness, Sleep Med Clin. 2010
REM/Deep Sleep/Light Sleep
There are four stages of sleep, described as follows:16Aakash K. Patel , Vamsi Reddy, John F. Araujo , Physiology, Sleep Stages, StatPearls Publishing. 202117Aakash K. Patel; Vamsi Reddy; John F. Araujo., Physiology, Sleep Stages, StatPearls Publishing; 2021
- Non-rapid eye movement Stage 1 (NREM-1) is a transition period between wakefulness and sleep. The body unwinds and relaxes in this stage by slowing down the heart rate, and the brain also slows down.
- Non-rapid eye movement Stage 2 (NREM-2) is the stage of light sleep where the body temperature drops and the brain produces rapid rhythmic waves known as sleep spindles.
- Non-rapid eye movement Stage 3 (NREM-3) is a transitory stage between light sleep and deep sleep where the muscles of the body relax completely and the brain starts producing delta waves.
- Rapid eye movement (REM) is the final stage of the sleep cycle where the body becomes immobilized and the eyes move rapidly. The activity of the brain is similar to awake hours and dreams occur in this stage.
The Dangers of Sleep Deprivation
Sleep deprivation is linked to heart attack, stroke, and increased risk of other cardiovascular disorders.18Qiao He, Peng Zhang, Guangxiao Li, Huixu Dai, Jingpu Shi, The association between insomnia symptoms and risk of cardio-cerebral vascular events: A meta-analysis of prospective cohort studies, Sage Journal. 2017
Sleep deprivation is associated with mood swings, gaps in memory, and compromised decision-making skills.19Torbjörn Akerstedt, Göran Kecklund, Jan Selén, Disturbed sleep and fatigue as predictors of return from long-term sickness absence, Ind Health. 2010 Chronic sleep deprivation increases the risk of development of Alzheimer’s disease and dementia with increasing age.20Ehsan Shokri-Kojori , Gene-Jack Wang , Corinde E Wiers , Sukru B Demiral , Min Guo , Sung Won Kim , Elsa Lindgren , Veronica Ramirez , Amna Zehra , Clara Freeman , Gregg Miller, Peter Manza , Tansha Srivastava , Susan De Santi , Dardo Tomasi , Helene Benveniste , Nora D Volkow, β-Amyloid accumulation in the human brain after one night of sleep deprivation, Proc Natl Acad Sci U S A. 2018
Metabolism and Obesity
Deprivation of sleep is linked to a reduction in leptin, which is an appetite-suppressing hormone, and an increase in ghrelin, which is an appetite stimulant.21Dieter Riemann , Christoph Nissen , Laura Palagini , Andreas Otte, Michael L Perlis , Kai Spiegelhalder, The neurobiology, investigation, and treatment of chronic insomnia, Lancet Neurol. 2015 This imbalance can lead to dysregulation of metabolism and an increased risk of obesity.22 Christopher B Cooper,Eric V Neufeld, Brett A Dolezal,and Jennifer L Martin , Sleep deprivation and obesity in adults: a brief narrative review,BMJ Open Sport Exerc Med. 2018
#1 Magnesium Product
Magnesium has been shown to improve sleep and manage several conditions, including stress, anxiety, and chronic inflammation.
Magnesium Breakthrough is a complex formulation that includes seven different forms of magnesium, such as chelate, citrate, bisglycinate, malate, aspartate, taurate, and orotate.
This is an important characteristic because different forms of magnesium can have different bioavailabilities; therefore, a complex formula consisting of different magnesium compounds is likely to increase the probability of gaining all the health benefits of magnesium.
Magnesium is a cofactor in more than 300 enzymatic reactions which occur in the human body and is essential in regulating all physiological and metabolic processes, including sleep homeostasis.
Heal while you sleep
Red light therapy, aka photobiomodulation, is a potent promoter of deep, restorative sleep.
The near-infrared light waves associated with red light therapy demonstrate the ability to penetrate cells below the skin and lower inflammation. This translates into increased healing and a sense of calm within the body.
In clinical studies, applying red light has shown the ability to improve all parameters of sleep including sleep quality, sleep duration, and sleep latency.
Sauna Space is my #1 choice for red light therapy since they use Low-EMF incandescent bulbs which better mimic the sun's natural light.
#1 Nootropic Stack for Sleep
Qualia Night is a sleep-specific nootropic blend from Neurohacker, the maker’s of Qualia Mind.
This formula includes 25 ingredients that are each proven to induce deep, restorative sleep.
Qualia Night’s potent mix of nootropics, vitamins, herbs, amino acids, and minerals support natural melatonin production along with nocturnal stem-cell function and BDNF biogenesis.
For you this means more profound sleep benefits and a sharper brain when awake.
CBD can support sleep and be used to help with a variety of sleep disorders, including insomnia.
The mechanism of action of CBD to regulate energy, mood, and sleep, is dependent on the receptors of the endocannabinoid system in the body.
Since there is a huge network of endocannabinoid receptors in our body, CBD can impact sleep homeostasis on my levels. For instance, CBD can improve the quality of sleep and help to improve the symptoms of REM sleep behavior disorder (RBD).
CBD can relieve the symptoms of stress and anxiety, which can in turn positively affect sleep patterns.
It’s best used in combination with a racetam, or acetylcholinesterase inhibitor like Huperzine A. Citicoline has also shown benefits for ADHD when used with caffeine. 23Steven E. Bruce, et al. Improvements in Concentration, Working Memory, and Sustained Attention Following Consumption of a Natural Citicoline-Caffeine Beverage, Int J Food Sci Nutr. 2014
Since citicoline has shown the ability to increase the release of dopamine, it is a prime candidate as a nootropic for ADHD. It can also improve mood and memory which are both often seen with ADHD.
Some people also find that this nootropic also increases their mood.
Ultramodern sleep aid helps you wake in the morning ready to perform
Performance Lab Sleep offers natural melatonin derived from tart cherry which effectively accelerates sleep onset.
It also relaxes the mind and body and provides relief from stress and pain.
It encourages the production of natural melatonin and serotonin which prepare the body for sleep.
It also contains some forms of magnesium which promote sleep-supportive muscle relaxation.
First developed as a wakefulness-promoting drug to combat narcolepsy, Adrafinil helps with ADHD according to preliminary research.24Modafinil for cognitive neuroenhancement in healthy non-sleep-deprived subjects: A systematic review, Eur Neuropsychopharmacol. 2015 25Milgram NW, et al. Oral administration of adrafinil improves discrimination learning in aged beagle dogs, Pharmacol Biochem Behav. 2000
This nootropic can help you stay awake and alert over long periods. It seems to modulate the dopamine system, which might help people living with ADHD stay on task.26Lindsay SE, Gudelsky GA, Heaton PC. Use of modafinil for the treatment of attention deficit/hyperactivity disorder, Ann Pharmacother. 2006
Learn more about adrafinil for attention-deficit/hyperactivity disorder and more.
Promotes a healthy circadian rhythm so that you can sleep deeper.
This essential oil formula includes sleep-friendly oils such as Balsam of Peru (Myroxylon balsamum), Lavender (Lavandula angustifolia), Melaleuca (Melaleuca quinquinervera ct Cineole), Myrtle (Myrtus communis), Myrrh (Commiphora myrrha), and more. Each of these natural, organic therapeutic oils help induce a state of calm and restfulness to help induce sleep.
Together, this blend is a potent stimulator of melatonin and helps rebalance your natural circadian rhythm..
Simply apply a few drops to the skin before bed for best results.
Regulates sleep cycle and helps you experience calm, promotes rest
Delta 8 THC interacts with the body's endocannabinoid system and can provide you the relaxation that induces sleep.
Regular use of Delta 8 THC can help you fall asleep more quickly and stay asleep for longer hours throughout the night.
Some scientific studies have concluded that delta-8 might potentially have clinically useful sedative and hypnotic properties which may be beneficial for patients diagnosed with sleeping disorders.
Delta-8 also has analgesic and anti-inflammatory effects which further contribute to the improvement of quality of sleep.
#1 Nootropic For Beginners
- Mind Lab Pro is my top stack choice for combatting ADHD.
- It's 11 high-potency ingredients can improve your ability to focus and concentrate without overstimulating your nervous system.
- The nootropics in this formula boost focus and concentration by enhancing acetylcholine, dopamine, and GABA.
- Adaptogens like Rhodiola and Bacopa increase mental energy while lowering your stress response.
- Compared to ADHD drugs, this stack isn't addictive and won't leave you feeling overstimulated.
- The supplements themselves are 3rd party tested and free of excess fillers and toxic ingredients.
- I love this stack for nootropic newbies and experienced nootropic users alike.
Holistic stamina and stress support
L-ornithine helps in promoting restful sleep and enhancing the quality of sleep.
L-ornithine modulates the GABA system and lowers stress hormones in the body, which induces a state of relaxation.
In addition to reducing mental stress levels, L-ornithine also buffers the levels of ammonia toxicity by disposing of excess nitrogen which reduces the levels of metabolic stress.
It is an all-natural supplement and has a wide variety of benefits which are mostly associated with stress relief, sleep improvement, and mood enhancement.